Introduction

The 2025 NFL season kicks off with a bang as the Dallas Cowboys visit the Philadelphia Eagles on Thursday, September 4 at 08:20 PM ET. This iconic NFC East rivalry sets the tone for the year ahead, with both teams eager to make a statement in Week 1. For the Eagles, it’s about defending their status as division heavyweights; for the Cowboys, it’s an opportunity to disrupt the narrative early.

Game Time

Primetime matchups always carry extra weight—and there’s no better spotlight than the Thursday night opener. Under the bright lights, both squads will aim to deliver a performance that fuels momentum into the long grind of the NFL season.

Moneyline Odds

Dallas Cowboys: +240
Philadelphia Eagles: -303

Bookmakers clearly favor the Eagles in this one, but as with any season opener, expect the unexpected—especially in a rivalry this intense.

Team Analysis

Dallas Cowboys

Starting the season on the road against a fierce division rival is no easy task. The Cowboys will need to overcome early jitters and execute flawlessly. While they bring athleticism and firepower, consistency has often eluded them. Their offensive line will be tested early by the Eagles’ aggressive front, and any early-season miscues could be costly.

Philadelphia Eagles

The Eagles enter Week 1 with confidence and continuity. Their balanced offense and physical defense give them the edge in matchups like this. While it’s only the first game, Philadelphia knows how crucial it is to strike early in a competitive division. Look for the Eagles to dictate tempo, control possession, and make the most of their home-field advantage.

Betting Prediction

While Week 1 always invites surprises, the Eagles have the tools to secure a strong opening victory. Their roster depth, system familiarity, and home crowd energy should carry them through. At -303, the Eagles are the safer bet for those looking for a confident pick to start the season. The Cowboys at +240 provide value for long-shot bettors, but the odds reflect the uphill climb they’ll face.

Bookmakers

You can place bets on this marquee Week 1 showdown at top platforms like DraftKings, LowVig.ag, BetOnline.ag, BetMGM, FanDuel, BetRivers, and Fanatics.

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