Prediction Details

MLB Prediction: New York Yankees vs St. Louis Cardinals (Saturday, August 16 at 07:15 PM ET)

Introduction

Updated

More MLB picks: New York Yankees · St. Louis Cardinals

The Yankees enter this interleague matchup against the Cardinals with steadier recent form, going 3-2 in their last five while averaging 4.2 runs per game, compared to St. Louis producing just 2.8 RPG in the same span. This MLB prediction leans heavily on the fact that New York Yankees’ offense has been more reliable while St. Louis continues to stall at the plate. With the Yankees holding a stronger overall record and already grabbing the first head-to-head meeting, the betting edge is clear on their side as they look to control tempo in a low-scoring environment.

Game Time

Starts in 5h 12m

Opening pitch at Saturday, August 16 at 07:15 PM ET inside Busch Stadium, deep alleys keep runs in check.

Odds & Spread Line

  • New York Yankees: -143
  • St. Louis Cardinals: +123

Total: 7.5

  • Run Line — New York Yankees: -1.5 (+114)
  • Run Line — St. Louis Cardinals: +1.5 (-137)

Latest Team Records

New York Yankees: 65-57 (Win %: 0.533)
St. Louis Cardinals: 61-62 (Win %: 0.496)

Injury Report

New York Yankees are missing Ryan Yarbrough (Oblique), listed as 15-Day-IL.

The St. Louis Cardinals are currently healthy with no major injury concerns.

Key Player Stats

New York Yankees

  • Aaron Judge: 0.33 AVG, 38 HR, 89 RBI
  • Cody Bellinger: 0.267 AVG, 22 HR, 69 RBI
  • Giancarlo Stanton: 0.299 AVG, 12 HR, 34 RBI

St. Louis Cardinals

  • Alec Burleson: 0.279 AVG, 15 HR, 54 RBI
  • Willson Contreras: 0.255 AVG, 16 HR, 65 RBI
  • Ivan Herrera: 0.294 AVG, 10 HR, 42 RBI

Team Analysis

New York Yankees

The Yankees’ 3-2 mark in their last five games shows a group capable of stabilizing in tight contests, even when offensive output is modest. Their 4.2 RPG in that stretch sits above the Cardinals’ recent pace, highlighting a more consistent scoring profile. Aaron Judge’s power presence sets the tone, while the lineup benefits from complementary production that keeps them competitive on the road despite a 28-32 away record.

Over the last 10 games, New York has split 5-5 with 3.7 RPG, reflecting a balanced but steady rhythm. Cody Bellinger’s ability to drive in runs has been critical to sustaining pressure, while Giancarlo Stanton’s timely hits provide depth beyond the top of the order. Against an opponent struggling to generate offense, the Yankees’ steadier run production and stronger record make them the more reliable betting side.

  • Batting Average: 0.249
  • Total Runs Scored: 616
  • Home Runs: 192
  • OBP: 0.329
  • SLG: 0.445
  • OPS: 0.774
  • ERA: 4.01
  • WHIP: 1.25

Away Record: 28-32 • Home Record: 37-25
Last 5 Games: 3-2 (4.2 RPG)
Last 10 Games: 5-5 (3.7 RPG)


St. Louis Cardinals

The Cardinals’ 2-3 record in their last five games is backed by just 2.8 RPG, underscoring an offense that has lacked consistency. Alec Burleson has shown flashes of production, but the team overall has not been able to string together sustained scoring. Even with a winning 35-28 home record, their inability to capitalize on recent opportunities limits their betting appeal against a disciplined Yankees side.

Across the last 10 games, St. Louis sits at 5-5 with 3.4 RPG, which reinforces the narrative of a stagnant attack. Willson Contreras has driven in runs, yet the lineup remains overly reliant on sporadic contributions, and Ivan Herrera’s contact ability has not been enough to offset the lack of depth. With the offense sputtering and the Yankees already proving the upper hand in this series, the Cardinals enter this contest at a clear disadvantage.

  • Batting Average: 0.249
  • Total Runs Scored: 529
  • Home Runs: 115
  • OBP: 0.318
  • SLG: 0.386
  • OPS: 0.704
  • ERA: 4.18
  • WHIP: 1.28

Away Record: 26-34 • Home Record: 35-28
Last 5 Games: 2-3 (2.8 RPG)
Last 10 Games: 5-5 (3.4 RPG)


Head-to-Head History

New York Yankees lead 1–0 (Most recent game)

  • August 15, 2025: NYY 4 @ STL 3

Over/Under Trends

New York Yankees’ last 10 games have averaged 7.5 total runs, with 6 games that would have cleared today’s total of 7.5.

St. Louis Cardinals’ last 10 games have averaged 7.7 combined runs, with 4 games clearing the same number of 7.5.

Moneyline Betting Prediction

New York Yankees’ steadier production, stronger overall record, and ability to edge tight contests give them the decisive edge over a Cardinals team that has failed to convert home advantage into consistent wins. With Aaron Judge anchoring the lineup and complementary hitters like Cody Bellinger and Giancarlo Stanton providing balance, the Yankees are positioned to control the pace. Coupled with their head-to-head win yesterday, the data points squarely to the Yankees as the sharper side.

This sets up cleanly for the New York Yankees to finish on top.

Over/Under Prediction

In their last five, the St. Louis Cardinals have produced 2.8 RPG and the New York Yankees 4.2. That output frames how this total sets up.

These teams are combining for 7.0 runs per game recently — below the posted total of 7.5. That leans to a Under 7.5.

Bookmakers

Current odds sourced from: FanDuel, LowVig.ag, BetOnline.ag, Caesars, DraftKings, MyBookie.ag, BetMGM, Fanatics, Bovada, BetUS, BetRivers.

Parlamaz may earn affiliate commissions from links in this article.

MLB Predictions FAQ

How does Parlamaz make New York Yankees vs St. Louis Cardinals MLB predictions?

We use trusted data feeds and real-time odds to model each matchup. We weight the numbers that move lines—team form, matchup history, injuries, park factors, totals trends, and betting momentum—then compare our price to the market to find value. All signal, no noise. No paywalls.

What do moneyline, run line, and total mean?

Moneyline is who wins the game. Run line is a spread, usually ±1.5 runs. The total (over/under) is combined runs by both teams.

What’s a good price range for today’s pick (Aug 16, 2025)?

We list a target price in the post. If the market moves past that number, reduce stake size or pass instead of chasing worse odds.

How should I size my bets?

Use a consistent unit (about 1–2% of bankroll). Singles should be most of your volume. We like parlays — smart ones. Build them from real edges, keep legs tight (2–3), cap risk to 0.25–0.5u, and pass when the price isn’t there.

How often are picks updated?

Daily. We update for confirmed lineups, injuries, and market moves. Check back near first pitch for final notes.

John Tamburino

John TamburinoVerified

Lead Analyst — data-first, former college baseball.

John Tamburino grew up on travel baseball and three years of varsity basketball, then played college baseball before shifting to analytics. He still watches everything—from weekday tennis to UFC—and will never forget the Diamondbacks’ 2001 run. At Parlamaz, John blends trusted data feeds with matchup context to find real value—no fluff, no paywalls.