Prediction Details

MLB Prediction: Minnesota Twins vs Chicago White Sox (Saturday, August 23 at 07:10 PM ET)

Introduction

Updated

MIN @ CWSMIN -110CWS -110O/U 9.0
Market / Trend MIN CWS
Moneyline -110 -110
Total (O/U) 9.0
Run Line -1.5 (140) +1.5 (-164)
Last 5 RPG 5.0 6.4
Record 58–69 45–82
Lines: Caesars, FanDuel, Fanatics, MyBookie.ag

More MLB picks: Minnesota Twins · Chicago White Sox

The White Sox have dropped 8 of their last 10, and their struggles create a sharp contrast in this MLB prediction against a Twins team that has already taken four of the last five head-to-head meetings. Minnesota Twins’ offense has averaged 5.0 runs over the last five games while Chicago has put up 6.4, pointing toward a high-scoring environment. With both lineups producing above-average totals and the Twins owning the clear H2H edge, the betting angle leans firmly toward Minnesota and the Over.

Game Time

Starts in 17h 57m

Game time: Saturday, August 23 at 07:10 PM ET at Guaranteed Rate Field, power alleys invite damage.

Odds & Spread Line

  • Minnesota Twins: -110
  • Chicago White Sox: -110

Total: 9

  • Run Line — Minnesota Twins: -1.5 (+140)
  • Run Line — Chicago White Sox: +1.5 (-164)

Latest Team Records

Minnesota Twins: 58-69 (Win %: 0.457)
Chicago White Sox: 45-82 (Win %: 0.354)

Injury Report

Minnesota Twins are missing Simeon Woods Richardson (Illness), listed as 15-Day-IL; Christian Vazquez (Shoulder), listed as 10-Day-IL; David Festa (Shoulder), listed as 15-Day-IL. No other significant injuries are reported.

The Chicago White Sox are currently healthy with no major injury concerns.

Key Player Stats

Minnesota Twins

  • Byron Buxton: 0.27 AVG, 25 HR, 61 RBI
  • Brooks Lee: 0.249 AVG, 13 HR, 53 RBI
  • Trevor Larnach: 0.244 AVG, 16 HR, 50 RBI

Chicago White Sox

  • Lenyn Sosa: 0.271 AVG, 17 HR, 55 RBI
  • Mike Tauchman: 0.273 AVG, 8 HR, 34 RBI
  • Andrew Benintendi: 0.227 AVG, 14 HR, 47 RBI

Team Analysis

Minnesota Twins

The Twins have gone 2-3 in their last five and 3-7 across their last ten, showing inconsistency but still finding ways to generate offense at 5.0 runs per game most recently. Byron Buxton’s power presence has been a stabilizing factor, and his ability to change games with extra-base hits keeps Minnesota dangerous even when overall form dips. On the road, the Twins have been underwhelming, but their lineup has shown resilience against weaker pitching staffs, which matters against a White Sox team with a bottom-tier record.

Brooks Lee and Trevor Larnach have added balance to the middle of the order, ensuring the Twins are not overly reliant on a single bat. While their overall run production has cooled in the ten-game sample, the more recent five-game average suggests a rebound. Given Chicago’s defensive issues, Minnesota Twins’ hitters are positioned to capitalize, and their situational edge makes them the stronger side despite their uneven stretch.

  • Batting Average: 0.237
  • Total Runs Scored: 525
  • Home Runs: 146
  • OBP: 0.309
  • SLG: 0.395
  • OPS: 0.704
  • ERA: 4.25
  • WHIP: 1.28

Away Record: 26-38 • Home Record: 33-31
Last 5 Games: 2-3 (5.0 RPG)
Last 10 Games: 3-7 (3.8 RPG)


Chicago White Sox

The White Sox have stumbled badly with a 1-4 mark in their last five and 2-8 in their last ten, reflecting a team that has been unable to sustain momentum. Lenyn Sosa has been one of the few consistent producers, yet his contributions have not been enough to offset broader inefficiency. Even with a recent scoring bump at 6.4 runs per game in the last five, the lack of wins highlights a pitching staff unable to support the offense.

Mike Tauchman has provided steady contact skills, and Andrew Benintendi has chipped in power, but the overall lineup remains unreliable. Their home record shows persistent struggles, and defensive lapses continue to cost them games. Against a Minnesota side that has repeatedly handled them head-to-head, the White Sox’s inconsistency makes them a liability despite occasional offensive outbursts.

  • Batting Average: 0.231
  • Total Runs Scored: 490
  • Home Runs: 125
  • OBP: 0.301
  • SLG: 0.37
  • OPS: 0.671
  • ERA: 4.18
  • WHIP: 1.37

Away Record: 19-46 • Home Record: 26-37
Last 5 Games: 1-4 (6.4 RPG)
Last 10 Games: 2-8 (4.5 RPG)


Head-to-Head History

Minnesota Twins lead 4–1 (Last 5 games)

  • August 22, 2025: MIN 9 @ CHW 7
  • April 24, 2025: CHW 3 @ MIN 0
  • April 23, 2025: CHW 3 @ MIN 6
  • April 22, 2025: CHW 2 @ MIN 4
  • April 02, 2025: MIN 6 @ CHW 1

Over/Under Trends

Minnesota Twins’ last 10 games have averaged 9.3 total runs, with 4 games that would have cleared today’s total of 9.

Chicago White Sox’s last 10 games have averaged 9.9 combined runs, with 4 games clearing the same number of 9.

Moneyline Betting Prediction

Minnesota has asserted control in this matchup, winning four of the last five against Chicago while sustaining stronger offensive balance. The Twins’ ability to generate runs from multiple sources, coupled with the White Sox’s continued struggles at home and lack of consistency despite recent scoring, makes the visitors the sharper side. This game sets up for Minnesota to extend its dominance and secure another win.

Form and matchup edges favor the Minnesota Twins — back them.

Over/Under Prediction

In their last five, the Chicago White Sox have produced 6.4 RPG and the Minnesota Twins 5.0. That output frames how this total sets up.

These teams are combining for 11.4 runs per game recently — above the posted total of 9.0. That points toward the Over 9.0.

Bookmakers

Available at: FanDuel, MyBookie.ag, Fanatics, Caesars.

Parlamaz may earn affiliate commissions from links in this article.

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John Tamburino

John TamburinoVerified

Lead Analyst — data-first, former college baseball.

John Tamburino grew up on travel baseball and three years of varsity basketball, then played college baseball before shifting to analytics. He still watches everything—from weekday tennis to UFC—and will never forget the Diamondbacks’ 2001 run. At Parlamaz, John blends trusted data feeds with matchup context to find real value—no fluff, no paywalls.