Prediction Details

MLB Prediction: Cincinnati Reds vs San Diego Padres (Tuesday, September 9 at 09:40 PM ET)

Introduction

Updated

CIN @ SDCIN +158SD -196O/U 7.5
Market / Trend CIN SD
Moneyline +158 -196
Total (O/U) 7.5
Run Line +1.5 (-135) -1.5 (115)
Last 5 RPG 5.0 5.4
Record 72–71 78–65
Lines: BetMGM, BetOnline.ag, BetRivers, BetUS +7 more

More MLB picks: Cincinnati Reds · San Diego Padres

The Padres’ 44-25 home record compared to the Reds’ 32-38 road mark sets a clear betting preview angle for this matchup. Cincinnati Reds’ recent 2-3 stretch has shown uneven offense despite averaging 5.0 runs per game, while San Diego has steadied at 3-2 with 5.4 RPG over the same span. With both teams combining for double-digit scoring lately, this game lines up perfectly for a strong Over position and a confident lean toward San Diego on the moneyline.

Game Time

Starts in 11h 36m

This one goes at Tuesday, September 9 at 09:40 PM ET inside Petco Park, conservative scoring is typical.

Odds & Spread Line

  • Cincinnati Reds: +158
  • San Diego Padres: -196

Total: 7.5

  • Run Line — Cincinnati Reds: +1.5 (-135)
  • Run Line — San Diego Padres: -1.5 (+115)

Latest Team Records

Cincinnati Reds: 72-71 (Win %: 0.503)
San Diego Padres: 78-65 (Win %: 0.545)

Injury Report

Both teams are currently healthy with no major injury concerns.

Key Player Stats

Cincinnati Reds

  • Elly De La Cruz: 0.267 AVG, 19 HR, 80 RBI
  • Miguel Andujar: 0.314 AVG, 9 HR, 40 RBI
  • Austin Hays: 0.263 AVG, 14 HR, 63 RBI

San Diego Padres

  • Manny Machado: 0.28 AVG, 23 HR, 84 RBI
  • Ramon Laureano: 0.3 AVG, 23 HR, 71 RBI
  • Gavin Sheets: 0.264 AVG, 19 HR, 63 RBI

Team Analysis

Cincinnati Reds

The Reds have hovered near .500 all season but their 32-38 road record shows clear vulnerability away from home. Their last 5 games at 2-3 underline inconsistency, even while averaging 5.0 runs per contest. Elly De La Cruz has been a central run producer, but the supporting cast has not consistently elevated the offense in hostile environments.

Over the last 10 games, Cincinnati sits at 4-6 while averaging 5.3 RPG, a profile that signals volatility rather than momentum. Miguel Andujar’s steady contact skills and Austin Hays’ power contributions create offensive potential, yet the lack of sustained form has limited them from stringing wins together. With their current rhythm, this team enters San Diego as the less reliable betting side.

  • Batting Average: 0.247
  • Total Runs Scored: 650
  • Home Runs: 143
  • OBP: 0.317
  • SLG: 0.392
  • OPS: 0.709
  • ERA: 3.93
  • WHIP: 1.25

Away Record: 32-38 • Home Record: 40-34
Last 5 Games: 2-3 (5.0 RPG)
Last 10 Games: 4-6 (5.3 RPG)


San Diego Padres

The Padres’ 44-25 home record highlights their ability to control games at Petco Park, a crucial betting edge. Their 3-2 mark in the last 5 games with 5.4 RPG reflects a steadying offense that has been able to generate enough support for their pitching staff. Manny Machado’s consistent power presence has been a reliable anchor in the middle of the order, ensuring production in key spots.

Across the last 10, San Diego is 4-6 but still averaging 5.0 RPG, showing that run creation remains intact even when results lag. Ramon Laureano’s balanced mix of power and contact has complemented Gavin Sheets’ ability to drive in runs, giving this lineup multiple avenues to score. With superior home form and a deeper offensive base, the Padres are positioned as the stronger side in this matchup.

  • Batting Average: 0.252
  • Total Runs Scored: 614
  • Home Runs: 127
  • OBP: 0.322
  • SLG: 0.387
  • OPS: 0.71
  • ERA: 3.66
  • WHIP: 1.21

Away Record: 35-40 • Home Record: 44-25
Last 5 Games: 3-2 (5.4 RPG)
Last 10 Games: 4-6 (5.0 RPG)


Head-to-Head History

Tied 2–2 (Last 4 games)

  • September 08, 2025: CIN 3 @ SD 4
  • June 29, 2025: SD 2 @ CIN 3
  • June 28, 2025: SD 6 @ CIN 4
  • June 27, 2025: SD 1 @ CIN 8

Over/Under Trends

Cincinnati Reds’ last 10 games have averaged 11.1 total runs, with 7 games that would have cleared today’s total of 7.5.

San Diego Padres’ last 10 games have averaged 9.9 combined runs, with 7 games clearing the same number of 7.5.

Moneyline Betting Prediction

San Diego Padres’ superior 44-25 home record, coupled with consistent run production from Manny Machado, Ramon Laureano, and Gavin Sheets, makes them the clear betting side. Cincinnati Reds’ 32-38 road struggles and uneven recent form reinforce the advantage, while the Padres’ balanced offense ensures they control this matchup with authority.

The San Diego Padres are the sharp side on form and splits.

Over/Under Prediction

In their last five, the San Diego Padres have produced 5.4 RPG and the Cincinnati Reds 5.0. That output frames how this total sets up.

These teams are combining for 10.4 runs per game recently — above the posted total of 7.5. That points toward the Over 7.5.

Bookmakers

These lines come from: FanDuel, LowVig.ag, BetOnline.ag, Caesars, MyBookie.ag, BetMGM, Bovada, BetRivers, BetUS, Fanatics, DraftKings.

Parlamaz may earn affiliate commissions from links in this article.

MLB Predictions FAQ

How should I size my bets?

Use a consistent unit (about 1–2% of bankroll). Singles should be most of your volume. We like parlays—smart ones. Keep legs tight (2–3), cap risk to 0.25–0.5u, and pass when the price isn’t there.

What do moneyline, run line, and total mean?

Moneyline is who wins the game. Run line is a spread, usually ±1.5 runs. The total (over/under) is combined runs by both teams.

John Tamburino

John TamburinoVerified

Lead Analyst — data-first, former college baseball.

John Tamburino grew up on travel baseball and three years of varsity basketball, then played college baseball before shifting to analytics. He still watches everything—from weekday tennis to all major league sports—and will never forget the Diamondbacks’ World Series run. At Parlamaz, John blends trusted data feeds with matchup context to find real value—no fluff, no paywalls.