- August 21, 2025
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MLB Prediction: Cincinnati Reds vs Arizona Diamondbacks (Friday, August 22 at 09:40 PM ET)
Introduction
Market / Trend | CIN | ARI |
---|---|---|
Moneyline | +115 | -141 |
Total (O/U) | 9.0 | |
Run Line | +1.5 (-175) | -1.5 (150) |
Last 5 RPG | 3.8 | 4.4 |
Record | 67–61 | 62–66 |
Lines: BetMGM, BetOnline.ag, BetRivers, BetUS +7 more |
More MLB picks: Cincinnati Reds · Arizona Diamondbacks
Cincinnati has surged into this matchup with a 6-4 mark over its last 10 games, averaging 5.6 runs per outing, while Arizona has split its last 10 at 5-5 with a lower scoring pace. That recent form provides a clear betting preview, highlighting the Reds’ steadier production and the Diamondbacks’ inconsistency. With Cincinnati holding the stronger overall record and having dominated the recent head-to-head series, the edge tilts firmly toward the visiting side in a game where runs are expected to stay under the posted total.
Game Time
The action begins at Friday, August 22 at 09:40 PM ET inside Chase Field, roof conditions stabilize totals.
Odds & Spread Line
- Cincinnati Reds: +115
- Arizona Diamondbacks: -141
Total: 9
- Run Line — Cincinnati Reds: +1.5 (-175)
- Run Line — Arizona Diamondbacks: -1.5 (+150)
Latest Team Records
Cincinnati Reds: 67-61 (Win %: 0.523)
Arizona Diamondbacks: 62-66 (Win %: 0.484)
Injury Report
The Cincinnati Reds are currently healthy with no major injury concerns.
Arizona Diamondbacks are missing Gabriel Moreno (Finger), listed as 60-Day-IL; Ryan Thompson (Shoulder), listed as 15-Day-IL; Anthony DeSclafani (Thumb), listed as 15-Day-IL. No other significant injuries are reported.
Key Player Stats
Cincinnati Reds
- Elly De La Cruz: 0.273 AVG, 19 HR, 76 RBI
- Miguel Andujar: 0.313 AVG, 9 HR, 38 RBI
- Noelvi Marte: 0.306 AVG, 10 HR, 40 RBI
Arizona Diamondbacks
- Geraldo Perdomo: 0.287 AVG, 13 HR, 81 RBI
- Ketel Marte: 0.293 AVG, 23 HR, 56 RBI
- Corbin Carroll: 0.253 AVG, 27 HR, 65 RBI
Team Analysis
Cincinnati Reds
The Reds have gone 3-2 across their last five games, showing balanced scoring with 3.8 runs per outing. On the road, their 31-32 record demonstrates competitiveness that travels well, particularly when paired with a strong bullpen ERA of 3.79. Elly De La Cruz continues to anchor the lineup with impactful production, giving Cincinnati a reliable offensive spark in tight games.
Over their last 10 games, the Reds have averaged 5.6 runs while going 6-4, a trend that highlights their ability to sustain pressure against opposing staffs. Miguel Andujar has provided steady contact hitting, while Noelvi Marte adds depth that forces pitchers to navigate a dangerous middle order. With consistency across multiple bats and a pitching staff keeping opponents in check, Cincinnati enters this contest as the more trustworthy side.
- Batting Average: 0.248
- Total Runs Scored: 581
- Home Runs: 127
- OBP: 0.318
- SLG: 0.392
- OPS: 0.71
- ERA: 3.79
- WHIP: 1.23
Away Record: 31-32 • Home Record: 36-29
Last 5 Games: 3-2 (3.8 RPG)
Last 10 Games: 6-4 (5.6 RPG)
Arizona Diamondbacks
Arizona has been inconsistent, going 2-3 across its last five games while averaging 4.4 runs. At home, their 32-31 record reflects mediocrity rather than dominance, leaving them vulnerable against sharper opponents. Geraldo Perdomo’s run production has been a bright spot, but uneven support around him has left games slipping late.
Across the last 10 contests, the Diamondbacks are just 5-5, producing 4.8 runs per game, a middle-of-the-pack output that fails to separate them from stronger competition. Ketel Marte’s power remains a threat, but with Corbin Carroll’s efficiency dipping, the lineup has lacked balance. Combined with a 4.55 ERA that too often puts them behind early, Arizona enters this matchup with less reliable form than their opponent.
- Batting Average: 0.251
- Total Runs Scored: 628
- Home Runs: 178
- OBP: 0.325
- SLG: 0.439
- OPS: 0.765
- ERA: 4.55
- WHIP: 1.33
Away Record: 30-35 • Home Record: 32-31
Last 5 Games: 2-3 (4.4 RPG)
Last 10 Games: 5-5 (4.8 RPG)
Head-to-Head History
Cincinnati Reds lead 3–0 (Last 3 games)
- June 08, 2025: ARI 2 @ CIN 4
- June 07, 2025: ARI 1 @ CIN 13
- June 06, 2025: ARI 3 @ CIN 4
Over/Under Trends
Cincinnati Reds’ last 10 games have averaged 9.4 total runs, with 4 games that would have cleared today’s total of 9.
Arizona Diamondbacks’ last 10 games have averaged 9.3 combined runs, with 6 games clearing the same number of 9.
Moneyline Betting Prediction
Cincinnati Reds’ 6-4 surge over its last 10 games, paired with a winning head-to-head sweep of Arizona earlier this season, shows a clear performance gap. The Reds have proven more efficient offensively and steadier on the mound, while the Diamondbacks’ home record has failed to inspire confidence. With production spread across multiple bats and a stronger recent scoring profile, Cincinnati is the sharper side to back outright.
The Cincinnati Reds at +115 fit a live underdog profile on recent numbers.
Over/Under Prediction
Recent five-game scoring: the Arizona Diamondbacks are at 4.4 RPG and the Cincinnati Reds at 3.8 — a useful baseline against the total.
These teams are combining for 8.2 runs per game recently — below the posted total of 9.0. That points toward the Under 9.0.
Bookmakers
Data pulled from: FanDuel, MyBookie.ag, LowVig.ag, BetOnline.ag, Caesars, DraftKings, Bovada, BetUS, BetMGM, BetRivers, Fanatics.
Parlamaz may earn affiliate commissions from links in this article.
MLB Predictions FAQ
What do moneyline, run line, and total mean?
Moneyline is who wins the game. Run line is a spread, usually ±1.5 runs. The total (over/under) is combined runs by both teams.
How often are picks updated?
Daily. We update for confirmed lineups, injuries, and market moves. Check back near first pitch for final notes.

John TamburinoVerified
Lead Analyst — data-first, former college baseball.
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