- August 28, 2025
- Views 22
MLB Prediction: San Diego Padres vs Minnesota Twins (Friday, August 29 at 08:10 PM ET)
Introduction
Market / Trend | SD | MIN |
---|---|---|
Moneyline | -127 | +110 |
Total (O/U) | 8.5 | |
Run Line | -1.5 (130) | +1.5 (-155) |
Last 5 RPG | 4.6 | 4.4 |
Record | 75–59 | 60–73 |
Lines: BetMGM, BetOnline.ag, BetRivers, BetUS +7 more |
More MLB picks: San Diego Padres · Minnesota Twins
Minnesota Twins’ last 10 contests have averaged 11.2 combined runs, a signal that this interleague matchup between the American League Twins and National League Padres sets up as an actionable MLB prediction for bettors targeting the total. San Diego has been steady with 6 wins in its last 10, but its away record of 32-37 exposes vulnerability outside of home comfort. Minnesota Twins’ offense, powered by Byron Buxton’s 27 home runs, has shown enough punch at home to tilt the moneyline edge in their favor despite a weaker overall record. The numbers point clearly toward Minnesota and a higher-scoring result.
Game Time
Set for Friday, August 29 at 08:10 PM ET inside Target Field, carry is often trimmed.
Odds & Spread Line
- San Diego Padres: -127
- Minnesota Twins: +110
Total: 8.5
- Run Line — San Diego Padres: -1.5 (+130)
- Run Line — Minnesota Twins: +1.5 (-155)
Latest Team Records
San Diego Padres: 75-59 (Win %: 0.56)
Minnesota Twins: 60-73 (Win %: 0.451)
Injury Report
Both teams are currently healthy with no major injury concerns.
Key Player Stats
San Diego Padres
- Manny Machado: 0.288 AVG, 21 HR, 78 RBI
- Ramon Laureano: 0.296 AVG, 21 HR, 66 RBI
- Ryan O’Hearn: 0.28 AVG, 16 HR, 53 RBI
Minnesota Twins
- Byron Buxton: 0.269 AVG, 27 HR, 64 RBI
- Brooks Lee: 0.249 AVG, 14 HR, 56 RBI
- Trevor Larnach: 0.242 AVG, 16 HR, 51 RBI
Team Analysis
San Diego Padres
The Padres enter at 75-59 with a winning percentage of .56, but recent results indicate uneven rhythm. Their last 5 games show a 2-3 mark with 4.6 runs per game, which signals inconsistency and a lack of finishing power in close contests. Manny Machado remains a central piece of their offensive identity, yet the road record of 32-37 shows this lineup does not travel effectively.
Over the last 10 games, San Diego has gone 6-4 with 4.9 runs per game, reflecting a team that can put runs together but struggles to sustain momentum away from home. Ramon Laureano has provided reliable production, but the lineup has not consistently translated that into road victories. With Ryan O’Hearn adding depth but the team’s away form dragging, the Padres look vulnerable against a motivated home side.
- Batting Average: 0.252
- Total Runs Scored: 564
- Home Runs: 116
- OBP: 0.322
- SLG: 0.386
- OPS: 0.707
- ERA: 3.6
- WHIP: 1.19
Away Record: 32-37 • Home Record: 43-22
Last 5 Games: 2-3 (4.6 RPG)
Last 10 Games: 6-4 (4.9 RPG)
Minnesota Twins
The Twins’ season mark of 60-73 is underwhelming, but their home record of 33-31 demonstrates stability at Target Field. Their last 5 games finished at 1-4 with 4.4 runs per game, showing a slump that demands an offensive spark. Byron Buxton’s power at the plate is the key lever to reversing that trend, especially against a traveling opponent with vulnerability away from home.
Across their last 10 games, Minnesota is 3-7 with 4.7 runs per game, but Brooks Lee and Trevor Larnach have chipped in enough production to keep the lineup competitive. While the win column has lagged, the consistent scoring profile suggests their offense is better than the record indicates. At home, where they play more confidently, this group is positioned to outperform expectations and seize value against San Diego.
- Batting Average: 0.238
- Total Runs Scored: 556
- Home Runs: 159
- OBP: 0.31
- SLG: 0.398
- OPS: 0.708
- ERA: 4.44
- WHIP: 1.31
Away Record: 27-42 • Home Record: 33-31
Last 5 Games: 1-4 (4.4 RPG)
Last 10 Games: 3-7 (4.7 RPG)
Head-to-Head History
No recent matchups between these teams in 2025.
Over/Under Trends
San Diego Padres’ last 10 games have averaged 8.8 total runs, with 5 games that would have cleared today’s total of 8.5.
Minnesota Twins’ last 10 games have averaged 11.2 combined runs, with 8 games clearing the same number of 8.5.
Moneyline Betting Prediction
Minnesota Twins’ ability to generate consistent run totals at home, even during a 3-7 stretch, positions them as the sharper side against a San Diego roster that has struggled to translate production into road wins. With Buxton anchoring the lineup and supporting bats like Lee and Larnach contributing, the Twins’ offensive ceiling at Target Field outweighs recent losses and makes them the preferred moneyline play. This is a spot where Minnesota Twins’ home edge aligns with their scoring profile for a decisive advantage.
We rate the Minnesota Twins at +110 as the right side at current form.
Over/Under Prediction
In their last five, the Minnesota Twins have produced 4.4 RPG and the San Diego Padres 4.6. That output frames how this total sets up.
These teams are combining for 9.0 runs per game recently — above the posted total of 8.5. That points toward the Over 8.5.
Bookmakers
You’ll find these markets at: FanDuel, BetOnline.ag, LowVig.ag, Caesars, DraftKings, MyBookie.ag, Bovada, BetUS, BetMGM, Fanatics, BetRivers.
Parlamaz may earn affiliate commissions from links in this article.
MLB Predictions FAQ
How often are picks updated?
Daily. We update for confirmed lineups, injuries, and market moves. Check back near first pitch for final notes.
What’s a good price range for today’s pick (Aug 29, 2025)?
We list a target price in the post. If the market moves past that number, reduce stake size or pass instead of chasing worse odds.

John TamburinoVerified
Lead Analyst — data-first, former college baseball.
More MLB Predictions
- MLB Predictions
- August 28, 2025
- Views 21
MLB Prediction: St. Louis Cardinals vs Cincinnati Reds
- MLB Predictions
- August 28, 2025
- Views 21
MLB Prediction: Seattle Mariners vs Cleveland Guardians (Friday,
- MLB Predictions
- August 28, 2025
- Views 23
MLB Prediction: Arizona Diamondbacks vs Los Angeles Dodgers
- MLB Predictions
- August 28, 2025
- Views 23
MLB Prediction: Atlanta Braves vs Philadelphia Phillies (Friday,
- MLB Predictions
- August 28, 2025
- Views 23