Prediction Details

MLB Prediction: San Diego Padres vs New York Mets (Tuesday, September 16 at 07:10 PM ET)

Introduction

Updated

SD @ NYMSD -108NYM -114O/U 8.5
Market / Trend SD NYM
Moneyline -108 -114
Total (O/U) 8.5
Run Line -1.5 (154) +1.5 (-190)
Last 5 RPG 5.0 3.4
Record 82–68 77–73
Lines: BetMGM, BetOnline.ag, BetRivers, BetUS +7 more

More MLB picks: San Diego Padres · New York Mets

The Mets enter this matchup analysis with a sharp home record of 46-29, a decisive edge against a Padres side that has struggled on the road at 35-40. Recent scoring shows San Diego at 5.0 RPG in its last five compared to New York Mets’ 3.4, keeping combined output modest relative to the posted total. With the Padres inconsistent away from home and the Mets’ lineup anchored by power bats, the value tilts toward a disciplined New York win in a lower-scoring contest.

Game Time

Starts in 16h 47m

Coverage starts at Tuesday, September 16 at 07:10 PM ET at Citi Field, a pitcher-leaning venue with muted carry.

Odds & Spread Line

  • San Diego Padres: -108
  • New York Mets: -114

Total: 8.5

  • Run Line — San Diego Padres: -1.5 (+154)
  • Run Line — New York Mets: +1.5 (-190)

Latest Team Records

San Diego Padres: 82-68 (Win %: 0.547)
New York Mets: 77-73 (Win %: 0.513)

Injury Report

Both teams are currently healthy with no major injury concerns.

Key Player Stats

San Diego Padres

  • Manny Machado: 0.277 AVG, 25 HR, 88 RBI
  • Ramon Laureano: 0.286 AVG, 23 HR, 75 RBI
  • Fernando Tatis Jr.: 0.264 AVG, 22 HR, 65 RBI

New York Mets

  • Pete Alonso: 0.266 AVG, 34 HR, 117 RBI
  • Juan Soto: 0.262 AVG, 40 HR, 98 RBI
  • Francisco Lindor: 0.263 AVG, 26 HR, 77 RBI

Team Analysis

San Diego Padres

The Padres have posted a 3-2 mark in their last 5 games, averaging 5.0 RPG, showing a steady but not dominant run of form. Their 6-4 stretch across the last 10 games reflects a team capable of producing offense, yet their 35-40 road record underlines recurring away inconsistencies. Manny Machado has been central to their production, but overall rhythm falters when the lineup travels.

Fernando Tatis Jr. and Ramon Laureano add balance to the order, but the offense has not consistently traveled, leaving key scoring gaps against stingy home opponents. Despite a respectable season record, the Padres’ away splits remain a liability in high-leverage betting spots. The data suggests limited upside against a Mets team that thrives at home in this environment.

  • Batting Average: 0.252
  • Total Runs Scored: 641
  • Home Runs: 135
  • OBP: 0.321
  • SLG: 0.388
  • OPS: 0.709
  • ERA: 3.64
  • WHIP: 1.2

Away Record: 35-40 • Home Record: 47-28
Last 5 Games: 3-2 (5.0 RPG)
Last 10 Games: 6-4 (4.9 RPG)


New York Mets

The Mets’ last 5 games show a 1-4 skid with 3.4 RPG, and their 2-8 mark across the last 10 confirms offensive struggles. However, their 46-29 home record highlights a clear venue advantage that offsets recent scoring droughts. Pete Alonso’s power presence ensures run potential remains dangerous even in low-output stretches.

Juan Soto and Francisco Lindor bring balance and situational hitting that can break through against visiting pitchers. While the team’s recent slump is notable, Citi Field’s environment and New York Mets’ proven home record create a decisive edge. Supporting trends point to a bounce-back spot, with the Mets’ home consistency outweighing the Padres’ road vulnerabilities.

  • Batting Average: 0.249
  • Total Runs Scored: 704
  • Home Runs: 203
  • OBP: 0.327
  • SLG: 0.426
  • OPS: 0.753
  • ERA: 4.01
  • WHIP: 1.34

Away Record: 31-44 • Home Record: 46-29
Last 5 Games: 1-4 (3.4 RPG)
Last 10 Games: 2-8 (3.0 RPG)


Head-to-Head History

San Diego Padres lead 3–0 (Last 3 games)

  • July 30, 2025: NYM 0 @ SD 5
  • July 29, 2025: NYM 1 @ SD 7
  • July 28, 2025: NYM 6 @ SD 7

Over/Under Trends

San Diego Padres’ last 10 games have averaged 8.3 total runs, with 4 games that would have cleared today’s total of 8.5.

New York Mets’ last 10 games have averaged 8.3 combined runs, with 6 games clearing the same number of 8.5.

Moneyline Betting Prediction

The Mets’ 46-29 home record paired with elite run producers like Alonso, Soto, and Lindor outweighs recent scoring struggles and positions them as the superior side. With the Padres’ inconsistency on the road and Citi Field’s tilt toward pitchers, the Mets hold the clear betting edge in this matchup.

Form and matchup edges favor the New York Mets — back them.

Over/Under Prediction

In their last five, the New York Mets have produced 3.4 RPG and the San Diego Padres 5.0. That output frames how this total sets up.

These teams are combining for 8.4 runs per game recently — right around the posted total of 8.5. That points toward the Under 8.5.

Bookmakers

Odds courtesy of: FanDuel, LowVig.ag, BetOnline.ag, Caesars, DraftKings, MyBookie.ag, BetUS, Bovada, Fanatics, BetMGM, BetRivers.

Parlamaz may earn affiliate commissions from links in this article.

MLB Predictions FAQ

What do moneyline, run line, and total mean?

Moneyline is who wins the game. Run line is a spread, usually ±1.5 runs. The total (over/under) is combined runs by both teams.

What’s a good price range for today’s pick (Sep 16, 2025)?

We list a target price in the post. If the market moves past that number, reduce stake size or pass instead of chasing worse odds.

How does Parlamaz make San Diego Padres vs New York Mets MLB predictions?

We use trusted data feeds and real-time odds to model each matchup. We weight the numbers that move lines—team form, matchup history, injuries, park factors, totals trends, and betting momentum—then compare our price to the market to find value. All signal, no noise. No paywalls.

John Tamburino

John TamburinoVerified

Lead Analyst — data-first, former college baseball.

John Tamburino grew up on travel baseball and three years of varsity basketball, then played college baseball before shifting to analytics. He still watches everything—from weekday tennis to all major league sports—and will never forget the Diamondbacks’ World Series run. At Parlamaz, John blends trusted data feeds with matchup context to find real value—no fluff, no paywalls.