Prediction Details

MLB Prediction: St. Louis Cardinals vs Colorado Rockies (Tuesday, July 22 at 08:40 PM ET)

Introduction

To say that there are significant differences between the St. Louis Cardinals and the Colorado Rockies would be an understatement. Coming into this American League and National League showdown, both teams find themselves at different points on the performance spectrum. Despite contrasting records and recent forms, this matchup promises to offer high stakes and much excitement for players and fans alike.

Game Time

Matchup set for Tuesday, July 22 at 08:40 PM ET in the hitter-friendly confines of Coors Field.

Moneyline Odds

St. Louis Cardinals: -145
Colorado Rockies: +120
Over/Under Line: 12.0

Latest Team Records

St. Louis Cardinals have a record of 51-49 with a win percentage of 0.51, while the Colorado Rockies hold a record of 24-75 with a win percentage of 0.242.

Injury Report

Both teams are currently healthy with no major injury concerns.

Key Player Stats

St. Louis Cardinals

  • Alec Burleson: 0.293 AVG, 12 HR, 44 RBI
  • Ivan Herrera: 0.313 AVG, 8 HR, 37 RBI
  • Brendan Donovan: 0.291 AVG, 8 HR, 37 RBI

Colorado Rockies

  • Hunter Goodman: 0.279 AVG, 18 HR, 55 RBI
  • Mickey Moniak: 0.267 AVG, 14 HR, 36 RBI
  • Jordan Beck: 0.275 AVG, 11 HR, 33 RBI

Team Analysis

St. Louis Cardinals

The St. Louis Cardinals have been navigating an up-and-down stretch, showing flashes of offensive potential but struggling to string together consistent momentum. Alec Burleson and Ivan Herrera have been key contributors, while Brendan Donovan has quietly added scoring depth. The team’s talent is evident, but execution in clutch situations remains an area for improvement.

While their home record reflects more stability, the road has posed challenges for St. Louis this season. Their ability to elevate against weaker opponents will be critical here. A bounce-back performance would not only boost morale but also serve as a catalyst for more cohesive play moving forward.

  • Batting Average: 0.251
  • Total Runs Scored: 451
  • Home Runs: 99
  • OPS: 0.713
  • ERA: 4.19
  • WHIP: 1.28

Away Record: 22-29 • Home Record: 29-20


Colorado Rockies

The Colorado Rockies continue to search for consistency as they navigate a tough season. Hunter Goodman and Mickey Moniak have been bright spots offensively, offering occasional sparks that keep the Rockies competitive. Jordan Beck has also contributed solid at-bats, but team-wide execution remains an ongoing issue.

With similar struggles at home and on the road, the Rockies will need to focus on fundamentals and limit mistakes to gain traction. Turning Coors Field into a reliable advantage is key — and a sharp, opportunistic showing in this matchup could help lay that foundation.

  • Batting Average: 0.233
  • Total Runs Scored: 353
  • Home Runs: 96
  • OPS: 0.677
  • ERA: 5.57
  • WHIP: 1.57

Away Record: 12-38 • Home Record: 12-37


Head-to-Head History

No recent matchups between these teams in 2025.

Moneyline Betting Prediction

The St. Louis Cardinals, despite their recent inconsistent performances, still have key players in form and the proven capability to pull off a win. Even though they are on the road, the Cardinals can rely on their solid offense to navigate through this matchup. Relying on their tactical approach, individual brilliance, and the hope of some momentum on their side, the Cardinals are poised to bounce back and secure a win.

Trust the St. Louis Cardinals at -145 to show why they’re the favorites here.

Bookmakers

Lines retrieved from: FanDuel, MyBookie.ag, BetOnline.ag, LowVig.ag, Caesars, DraftKings, Bovada, BetRivers, BetMGM, BetUS, Fanatics.

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