Introduction

The San Diego Padres and the St. Louis Cardinals are set to collide in a compelling National League showdown. The Padres strut into this duel with an impressive slate, while the Cardinals aim to leverage their offensive firepower to assert dominance. What’s certain is a highly contested showdown that will come down to key player performances, current form, and game day execution.

Game Time

First pitch will be thrown at Thursday, July 24 at 07:45 PM ET at pitcher-friendly Busch Stadium in St. Louis.

Moneyline Odds

San Diego Padres: +110
St. Louis Cardinals: -139
Over/Under Line: 8.5

Latest Team Records

San Diego Padres have a record of 55-47 with a win percentage of 0.539, while the St. Louis Cardinals hold a record of 52-51 with a win percentage of 0.505.

Injury Report

Both teams are currently healthy with no major injury concerns.

Key Player Stats

San Diego Padres

• Manny Machado: 0.285 AVG, 18 HR, 61 RBI
• Fernando Tatis Jr.: 0.262 AVG, 16 HR, 42 RBI
• Gavin Sheets: 0.254 AVG, 14 HR, 51 RBI

St. Louis Cardinals

• Alec Burleson: 0.293 AVG, 12 HR, 44 RBI
• Willson Contreras: 0.258 AVG, 13 HR, 57 RBI
• Ivan Herrera: 0.303 AVG, 8 HR, 37 RBI

Team Analysis

San Diego Padres

The Padres will look to regain their footing after a mediocre run in recent games, with a 2-3 record in their last five outings. The team, however, showcases a commendable fighting spirit, especially with key players like Manny Machado and Fernando Tatis Jr., delivering consistent performances. Their ability to capitalize on key plays could prove instrumental in scoring victories.

Furthermore, Gavin Sheets adds depth to the lineup with his left-handed power and consistent run production. While not always the star, his bat can be the spark that tips the scales in tight matchups.

• Batting Average: 0.246
• Total Runs Scored: 405
• Home Runs: 86
• OPS: 0.69
• ERA: 3.59
• WHIP: 1.23

Away Record: 24-29 • Home Record: 31-18
Last 5 Games: 2-3 (3.4 RPG)
Last 10 Games: 6-4 (3.8 RPG)

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St. Louis Cardinals

The St. Louis Cardinals, despite a recent 1-4 slide, aren’t to be taken lightly. The Cardinals have shown glimpses of offensive brilliance, largely due to standout performances from Alec Burleson, Willson Contreras, and Ivan Herrera. These key players hold the potential to ignite the team’s offensive power and swing the momentum in their favor.

Fortunately, the Cardinals have been much more effective at home, boasting a solid 29–20 record at Busch Stadium. Their ability to leverage that home field advantage could prove pivotal in turning recent struggles around. This matchup gives St. Louis a prime chance to regroup and build momentum in familiar territory.

• Batting Average: 0.253
• Total Runs Scored: 461
• Home Runs: 100
• OPS: 0.716
• ERA: 4.19
• WHIP: 1.28

Away Record: 23-31 • Home Record: 29-20
Last 5 Games: 1-4 (2.8 RPG)
Last 10 Games: 3-7 (4.1 RPG)

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Head-to-Head History

No recent matchups between these teams in 2025.

Over/Under Trends

San Diego Padres’ recent games have seen an average of 6.8 total runs scored per game over their last 10 matchups, with 4 games going over the total of 8.5.

St. Louis Cardinals’ recent games have averaged 9.1 total runs per game over their last 10 matchups, with 6 games going over the total of 8.5.

Moneyline Betting Prediction

Despite their recent form, the St. Louis Cardinals carry a notable offensive surge. Their key players are firing on all cylinders, spelling trouble for the Padres. Factor in their powerful home record and the Cardinals gain a formidable edge. Backed by their robust batting lineup and advantageous home field, the St. Louis Cardinals are primed for a return to victory.

Back the St. Louis Cardinals at -139 to deliver with confidence.

Over/Under Prediction

Averaging 2.8 runs per game lately, the St. Louis Cardinals are ramping up offensively, while the San Diego Padres are putting up 3.4. That could influence how this matchup shapes up against the total.

These teams are combining for 6.2 runs per game recently — below the posted total of 8.5, a crucial pivot point in betting markets. Our pick is Under 8.5.

Bookmakers

These lines come from: FanDuel, LowVig.ag, BetOnline.ag, Caesars, MyBookie.ag, Bovada, DraftKings, BetMGM, BetUS, Fanatics, BetRivers.

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