Introduction

Thursday evening will paint the stage for a classic American League showdown as the Cleveland Guardians cross paths with the Chicago White Sox. As the Guardians strive to make it above the .500 record mark, the White Sox aim to scrape their way out of a season-defining slump. This MLB clash promises to thrill fans while offering enticing betting opportunities.

Game Time

First pitch for the Cleveland Guardians vs. Chicago White Sox is set for 07:40 PM ET on Thursday, July 10.

Moneyline Odds

Cleveland Guardians: -127
Chicago White Sox: +115

Over/Under Line: 8.5

Latest Team Records

Cleveland Guardians have a record of 43-48 with a win percentage of 0.473, while the Chicago White Sox hold a record of 31-62 with a win percentage of 0.333.

Injury Report

Key injuries for the Cleveland Guardians include:

• Kyle Manzardo (Personal) – Status: bereavement. Manzardo isn’t in the lineup for Saturday’s game against the Tigers.
• Lane Thomas (Foot) – Status: 10-Day-IL. Thomas (foot) isn’t in the lineup for Saturday’s game against the Tigers.
• Will Brennan (Elbow) – Status: 60-Day-IL. The Guardians transferred Brennan (elbow) to the 60-day injured list Friday.

The Chicago White Sox are currently healthy with no major injury concerns.

Key Player Stats

Cleveland Guardians

• Jose Ramirez: 0.299 AVG, 16 HR, 44 RBI
• Steven Kwan: 0.292 AVG, 6 HR, 29 RBI
• Carlos Santana: 0.23 AVG, 10 HR, 38 RBI

Chicago White Sox

• Lenyn Sosa: 0.274 AVG, 4 HR, 17 RBI
• Miguel Vargas: 0.219 AVG, 10 HR, 34 RBI
• Luis Robert Jr.: 0.187 AVG, 8 HR, 32 RBI

Team Analysis

Cleveland Guardians

The Cleveland Guardians are exhibiting a steady upward stride, especially noticeable in their recent power hitting from Jose Ramirez and Steven Kwan. In terms of offensive rhythm, their performance demonstrates a balance of consistent scoring and timely power-hitting. Despite recent injuries, the team has managed to maintain a strong performance thanks to key contributors such as Carlos Santana, providing value on both sides of the plate.

Heading into this match-up against the White Sox, the Guardians will look to repeat their recent positive performance and post a third consecutive win, improving those inconsistent home and road records. Considering their last five games, they’ve averaged 4.6 runs per game, which is a promising sign of a potential scoring explosion against the struggling White Sox.

• Batting Average: 0.224
• Total Runs Scored: 329
• Home Runs: 90
• OPS: 0.661
• ERA: 3.99
• WHIP: 1.36

Home Record: 20-23 • Road Record: 23-25

Last 5 Games: W-W-W-L-L (4.6 runs per game)

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Chicago White Sox

The Chicago White Sox are finding themselves in a challenging spot, trying to engineer a turnaround amidst a battling season. Despite tough circumstances, notable performances have come from Lenyn Sosa and Miguel Vargas. Luis Robert Jr. will also need to step up his game, as his current average fails to reflect his full offensive potential.

Despite their struggles, the White Sox managed to sneak in two wins in their last five games, albeit surrounded by losses. Their inconsistent performance puts their offense in the spotlight, seeking to improve upon an average of 4.2 runs per game, which may prove to be difficult against the Guardians’ solid pitching lineup.

• Batting Average: .222
• Total Runs Scored: 316
• Home Runs: 71
• OPS: .642
• ERA: 4.17
• WHIP: 1.4

Home Record: 20-26 • Road Record: 11–36

Last 5 Games: W-L-L-L-W (4.2 runs per game)

Head-to-Head History

Chicago White Sox 0–3 Cleveland Guardians (Last 3 games)

• 2025-04-10: CHW 1 @ CLE 6
• 2025-04-09: CHW 2 @ CLE 3
• 2025-04-08: CHW 0 @ CLE 1

Over/Under Trends

Cleveland Guardians have averaged 8.2 runs per game over their last 6 games, with 2 games going over the total.

Chicago White Sox have averaged 7.0 runs per game over their last 6 games, with 3 games going over the total of 8.5.

Moneyline Betting Prediction

Drawing from their promising recent form and head-to-head history, the Cleveland Guardians at -127 are the favored choice. Encouraged by the Guardians’ superior form in their recent games and the effective offensive partnership of Ramirez and Kwan, backing the Guardians would seem to carry greater potential reward in this match-up.

Over/Under Betting Prediction

Given the scoring averages of both teams in their recent games, with both nearing the 8.5 run total, betting the over should be seriously considered. The Guardians’ recent games have seen an average total of 8.2 runs, while the White Sox have maintained an average of 7.0.

Pick: Over 8.5

Bookmakers

Current odds sourced from: FanDuel, LowVig.ag, BetOnline.ag, MyBookie.ag, Caesars, DraftKings, BetMGM, BetRivers, Bovada, Fanatics, BetUS.

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