Introduction

The Chicago Cubs and the Chicago White Sox are set to lock horns in a keenly anticipated American League and National League showdown. The Cubs are bringing their fiery road form into play, while the White Sox will be backing themselves to add another home win to their tally. This promises to be a thrilling matchup, marked by the signature flavor of the classic Cubs-Sox rivalry.

Game Time

The first pitch is scheduled for Saturday, July 26 at 07:10 PM ET in Guaranteed Rate Field, a park that can tilt toward overs.

Moneyline Odds

Chicago Cubs: -196
Chicago White Sox: +160
Over/Under Line: 9.0

Latest Team Records

Chicago Cubs have a record of 60-42 with a win percentage of 0.588, while the Chicago White Sox hold a record of 37-66 with a win percentage of 0.359.

Injury Report

Key injuries for the Chicago Cubs include:

• Miguel Amaya (Oblique) – Status: 10-Day-IL. Amaya (oblique) is expected to begin a rehab assignment Thursday, MLB.com reports.
• Eli Morgan (Elbow) – Status: 60-Day-IL. Morgan (elbow) began a rehab assignment in the rookie-level Arizona Complex League on Thursday.

The Chicago White Sox are currently healthy with no major injury concerns.

Key Player Stats

Chicago Cubs

• Pete Crow-Armstrong: 0.27 AVG, 27 HR, 74 RBI
• Seiya Suzuki: 0.256 AVG, 26 HR, 81 RBI
• Michael Busch: 0.284 AVG, 20 HR, 60 RBI

Chicago White Sox

• Lenyn Sosa: 0.264 AVG, 9 HR, 34 RBI
• Mike Tauchman: 0.283 AVG, 5 HR, 26 RBI
• Andrew Benintendi: 0.236 AVG, 11 HR, 37 RBI

Team Analysis

Chicago Cubs

Despite the odds being stacked against them due to key players’ injuries, the Cubs have displayed a steely resolve, especially on the road. Their away game consistency has been a vital contributor to their solid record. Players like Pete Crow-Armstrong and Seiya Suzuki have been paramount in maintaining the offensive rhythm, effectively silencing their opponents’ home crowds.

However, their recent form report paints a less-than-perfect picture, with a 1-4 record in the last five games. The Cubs will surely be pumping themselves to turn the tide and restore their winning rhythm, counting on the likes of Michael Busch to bolster the offensive line-up.

• Batting Average: 0.256
• Total Runs Scored: 537
• Home Runs: 152
• OPS: 0.77
• ERA: 3.86
• WHIP: 1.22

Away Record: 27-24 • Home Record: 33-19
Last 5 Games: 1-4 (4.0 RPG)
Last 10 Games: 5-5 (3.9 RPG)

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Chicago White Sox

The White Sox have been showing signs of resurgence recently, with an impressive 4-1 record in their last five outings. This surge can be attributed to the rise in form of key players such as Lenyn Sosa and Mike Tauchman, who are essential to the team’s offensive strategy.

Despite their recent surge, the White Sox remain vulnerable at home and will need to tighten up defensively to fend off the Cubs’ bats. Andrew Benintendi’s contribution to the team’s run scoring potential will be decisive in uplifting the team’s home performance.

• Batting Average: 0.224
• Total Runs Scored: 381
• Home Runs: 85
• OPS: 0.652
• ERA: 4.08
• WHIP: 1.38

Away Record: 16-37 • Home Record: 22-29
Last 5 Games: 4-1 (8.2 RPG)
Last 10 Games: 7-3 (7.3 RPG)

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Head-to-Head History

Chicago Cubs lead 3–1 (Last 4 games)

• 2025-07-25: CHC 5 @ CHW 12
• 2025-05-18: CHW 2 @ CHC 6
• 2025-05-17: CHW 3 @ CHC 7
• 2025-05-16: CHW 3 @ CHC 13

Over/Under Trends

Chicago Cubs’ last 10 games have averaged 9.2 total runs per game, with 4 of those going over the posted total of 9.0.

Chicago White Sox’s last 10 games have seen an average of 11.7 combined runs, with 6 games clearing the same line of 9.0.

Moneyline Betting Prediction

Considering their solid road record and the recent form of key players like Pete Crow-Armstrong and Seiya Suzuki, the Chicago Cubs appear set to stage a determined fightback from their recent slump. Their head-to-head record against the White Sox gives further weight to their winning potential. The early momentum may shift back and forth, but the Cubs’ experienced roster should ultimately tilt the game in their favor.

Back the Chicago Cubs to deliver with confidence.

Over/Under Prediction

The Chicago White Sox are scoring 8.2 runs per game across their last five, and the Chicago Cubs are at 4.0. Recent form suggests where this total might land.

These teams are combining for 12.2 runs per game recently — above the posted total of 9.0, a crucial pivot point in betting markets. That leans toward a Over 9.0 finish.

Bookmakers

Find these odds at: BetOnline.ag, LowVig.ag, FanDuel, Caesars, MyBookie.ag, DraftKings, BetMGM, BetUS, Fanatics, BetRivers, Bovada.

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