Prediction Details

MLB Prediction: Chicago Cubs vs Chicago White Sox (Friday, July 25 at 07:40 PM ET)

Introduction

As the summer heats up, so does the baseball field. Get ready for a thrilling American League and National League showdown between the Chicago Cubs and the Chicago White Sox. Given recent form and team compositions, this inter-city rivalry will certainly be an exciting one.

Game Time

First pitch will be thrown at Friday, July 25 at 07:40 PM ET at Guaranteed Rate Field, where power bats can thrive.

Moneyline Odds

Chicago Cubs: -185
Chicago White Sox: +150
Over/Under Line: 8.5

Latest Team Records

Chicago Cubs have been performing well this season with a record of 60-42 and a win percentage of 0.588. The Chicago White Sox, on the other hand, hold a record of 37-66, maintaining a win percentage of 0.359.

Injury Report

The game’s momentum could be influenced by key injuries to Cubs players, Eli Morgan and Porter Hodge. Thankfully, the Chicago White Sox are currently healthy with no major injury concerns.

Key Player Stats

Chicago Cubs

  • Pete Crow-Armstrong: 0.27 AVG, 27 HR, 74 RBI
  • Seiya Suzuki: 0.256 AVG, 26 HR, 81 RBI
  • Michael Busch: 0.284 AVG, 20 HR, 60 RBI

Chicago White Sox

  • Lenyn Sosa: 0.264 AVG, 9 HR, 34 RBI
  • Mike Tauchman: 0.283 AVG, 5 HR, 26 RBI
  • Andrew Benintendi: 0.236 AVG, 11 HR, 37 RBI

Team Analysis

Chicago Cubs

Despite key players nursing injuries, the Chicago Cubs carry noteworthy momentum in the league. Standout performances from players such as Pete Crow-Armstrong and Seiya Suzuki have played a vital role in the Cubs’ offensive drive, contributing to a consistent scoring rate. Michael Busch’s contributions cannot be discounted either, which altogether give the Cubs a lethal offensive combination.

Their performance on the road has been satisfactory but not exceptional, with an away record of 27 wins and 23 losses. Consistency has been a minor issue; despite their recent performance of 2 wins and 3 losses in their last five games, they have managed a 6 win and 4 loss record in their last 10 outings. All eyes will be on the Cubs as they look to bounce back from their slight dip in performance.

  • Batting Average: 0.256
  • Total Runs Scored: 537
  • Home Runs: 152
  • OPS: 0.77
  • ERA: 3.86
  • WHIP: 1.22

Away Record: 27-23 • Home Record: 33-19
Last 5 Games: 2-3 (4.2 RPG)
Last 10 Games: 6-4 (4.2 RPG)


Chicago White Sox

The Chicago White Sox have been showcasing solid form recently. At their home ground, they have capitalized on their strengths, making for an intriguing factor going into this game. Performers such as Lenyn Sosa and Mike Tauchman have added much-needed firepower to their batting lineup. Andrew Benintendi’s contribution has also been commendable, contributing consistently to their run rate.

Looking at their recent form of 4 victories in the last five games, we see an uptrend, displaying their ability to improve upon their home record of 21 wins and 29 losses. With this momentum, the team could pose a significant challenge to the Chicago Cubs.

  • Batting Average: 0.224
  • Total Runs Scored: 381
  • Home Runs: 85
  • OPS: 0.652
  • ERA: 4.08
  • WHIP: 1.38

Away Record: 16-37 • Home Record: 21-29
Last 5 Games: 4-1 (7.8 RPG)
Last 10 Games: 6-4 (6.3 RPG)


Head-to-Head History

Chicago White Sox 0–3 Chicago Cubs (Last 3 games)

  • 2025-05-18: CHW 2 @ CHC 6
  • 2025-05-17: CHW 3 @ CHC 7
  • 2025-05-16: CHW 3 @ CHC 13

Over/Under Trends

Chicago Cubs’ last 10 games have averaged 8.4 total runs per game, with 4 of those going over the posted total of 8.5.

Chicago White Sox’s last 10 games have seen an average of 10.0 combined runs, with 7 games clearing the same line of 8.5.

Moneyline Betting Prediction

Considering the recent performance and momentum of the Chicago Cubs, they seem poised to come out on top in this matchup. Paired with their strong record over the White Sox in recent history, it seems that backing the Cubs to win this game is where the smart money lies. With power hitters on board and a good run of form, it is a formidable pick to back the Chicago Cubs.

The Chicago Cubs at -185 look like a strong bet to handle business.

Over/Under Prediction

The Chicago White Sox are scoring 7.8 runs per game across their last five, and the Chicago Cubs are at 4.2. Recent form suggests where this total might land.

These teams are combining for 12.0 runs per game recently — above the posted total of 8.5, a crucial pivot point in betting markets. Our pick is Over 8.5.

Bookmakers

Find these odds at: FanDuel, LowVig.ag, BetOnline.ag, Caesars, DraftKings, BetMGM, MyBookie.ag, Bovada, BetRivers, BetUS, Fanatics.

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