Prediction Details

MLB Prediction: Cleveland Guardians vs Boston Red Sox (Tuesday, September 2 at 06:45 PM ET)

Introduction

Updated

CLE @ BOSCLE +210BOS -263O/U 8.0
Market / Trend CLE BOS
Moneyline +210 -263
Total (O/U) 8.0
Run Line +1.5 (-102) -1.5 (-117)
Last 5 RPG 3.8 3.8
Record 68–67 76–62
Lines: BetMGM, BetOnline.ag, BetRivers, BetUS +7 more

More MLB picks: Cleveland Guardians · Boston Red Sox

Boston’s steady 7–3 mark over the last 10 games contrasts sharply with Cleveland Guardians’ 4–6 skid, a clear signal for this MLB prediction. The Guardians have averaged just 2.5 runs per game across that stretch, showing prolonged offensive inconsistency, while the Red Sox have maintained 4.5 runs per game to stay firmly in the upper tier of the division. With both clubs combining for sub-8 totals in recent contests, the betting edge aligns with Boston on the moneyline and the Under on the total.

Game Time

Starts in 21h 33m

Game time: Tuesday, September 2 at 06:45 PM ET at Fenway Park, quirky angles shape extra-base hit potential.

Odds & Spread Line

  • Cleveland Guardians: +210
  • Boston Red Sox: -263

Total: 8

  • Run Line — Cleveland Guardians: +1.5 (-102)
  • Run Line — Boston Red Sox: -1.5 (-117)

Latest Team Records

Cleveland Guardians: 68-67 (Win %: 0.504)
Boston Red Sox: 76-62 (Win %: 0.551)

Injury Report

Both teams are currently healthy with no major injury concerns.

Key Player Stats

Cleveland Guardians

  • Jose Ramirez: 0.283 AVG, 26 HR, 68 RBI
  • Kyle Manzardo: 0.233 AVG, 23 HR, 60 RBI
  • Steven Kwan: 0.27 AVG, 10 HR, 43 RBI

Boston Red Sox

  • Trevor Story: 0.256 AVG, 22 HR, 84 RBI
  • Wilyer Abreu: 0.253 AVG, 22 HR, 69 RBI
  • Jarren Duran: 0.26 AVG, 14 HR, 76 RBI

Team Analysis

Cleveland Guardians

The Guardians enter this contest with a middling 68–67 record and an away split of 33–35 that reflects their inconsistency on the road. Their last 10 games produced only 2.5 runs per outing, signaling a clear offensive slump that undermines their ability to compete against higher-scoring lineups. While Jose Ramirez continues to be a reliable bat, the surrounding order has lacked sustained production in key spots.

Recent results show a 3–2 record over the last 5, but the run output of 3.8 per game still sits below league-average scoring levels. Kyle Manzardo provides power potential, yet the lineup’s inability to string together rallies has kept totals low. With Steven Kwan more contact-oriented, the Guardians’ attack leans small-ball, but without consistent run support, it is not enough to threaten a strong home side.

  • Batting Average: 0.223
  • Total Runs Scored: 519
  • Home Runs: 137
  • OBP: 0.294
  • SLG: 0.366
  • OPS: 0.659
  • ERA: 3.92
  • WHIP: 1.31

Away Record: 33-35 • Home Record: 35-33
Last 5 Games: 3-2 (3.8 RPG)
Last 10 Games: 4-6 (2.5 RPG)


Boston Red Sox

The Red Sox hold a 76–62 record and have been dominant at Fenway with a 43–27 home mark that emphasizes their reliability in this venue. Over their last 10 games, they have gone 7–3 while scoring 4.5 runs per contest, showing consistent offensive balance. Trevor Story has been the key run producer, giving this lineup a dependable middle-order presence that Cleveland lacks.

Recent form also shows a steady 3–2 over their last 5 with 3.8 runs per game, but the broader 10-game stretch confirms sustained rhythm. Wilyer Abreu has given them complementary power while Jarren Duran’s speed element keeps pressure on opposing defenses. With home-field advantage and a deeper lineup, Boston projects as the sharper betting side.

  • Batting Average: 0.252
  • Total Runs Scored: 678
  • Home Runs: 166
  • OBP: 0.323
  • SLG: 0.424
  • OPS: 0.748
  • ERA: 3.68
  • WHIP: 1.29

Away Record: 34-35 • Home Record: 43-27
Last 5 Games: 3-2 (3.8 RPG)
Last 10 Games: 7-3 (4.5 RPG)


Head-to-Head History

Boston Red Sox lead 3–1 (Last 4 games)

  • September 01, 2025: CLE 4 @ BOS 6
  • April 27, 2025: BOS 13 @ CLE 3
  • April 26, 2025: BOS 7 @ CLE 3
  • April 26, 2025: BOS 4 @ CLE 5

Over/Under Trends

Cleveland Guardians’ last 10 games have averaged 7.3 total runs, with 4 games that would have cleared today’s total of 8.

Boston Red Sox’s last 10 games have averaged 8.0 combined runs, with 4 games clearing the same number of 8.

Moneyline Betting Prediction

Boston’s 43–27 home record paired with a 7–3 surge over their last 10 games highlights a team playing with consistent rhythm. With multiple wins against Cleveland already this season and stronger run production from Trevor Story and Wilyer Abreu, the Red Sox project as the superior side to back in this matchup.

Confidence sits with the Boston Red Sox based on recent profiles.

Over/Under Prediction

Last five form shows the Boston Red Sox at 3.8 RPG and the Cleveland Guardians at 3.8, giving context for the number.

These teams are combining for 7.6 runs per game recently — below the posted total of 8.0. That points toward the Under 8.0.

Bookmakers

You’ll find these markets at: FanDuel, LowVig.ag, BetOnline.ag, Caesars, DraftKings, BetUS, Bovada, BetMGM, BetRivers, MyBookie.ag, Fanatics.

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MLB Predictions FAQ

How should I size my bets?

Use a consistent unit (about 1–2% of bankroll). Singles should be most of your volume. We like parlays—smart ones. Keep legs tight (2–3), cap risk to 0.25–0.5u, and pass when the price isn’t there.

What’s a good price range for today’s pick (Sep 02, 2025)?

We list a target price in the post. If the market moves past that number, reduce stake size or pass instead of chasing worse odds.

John Tamburino

John TamburinoVerified

Lead Analyst — data-first, former college baseball.

John Tamburino grew up on travel baseball and three years of varsity basketball, then played college baseball before shifting to analytics. He still watches everything—from weekday tennis to all major league sports—and will never forget the Diamondbacks’ World Series run. At Parlamaz, John blends trusted data feeds with matchup context to find real value—no fluff, no paywalls.