Prediction Details

MLB Prediction: San Francisco Giants vs San Diego Padres (Wednesday, August 20 at 09:40 PM ET)

Introduction

Updated

SF @ SDSF +131SD -147O/U 8.0
Market / Trend SF SD
Moneyline +131 -147
Total (O/U) 8.0
Run Line +1.5 (-165) -1.5 (140)
Last 5 RPG 3.8 2.8
Record 61–64 69–56
Lines: BetMGM, BetOnline.ag, BetRivers, BetUS, Bovada, Caesars, DraftKings, FanDuel, Fanatics, LowVig.ag, MyBookie.ag

More MLB picks: San Francisco Giants · San Diego Padres

San Diego Padres’ recent 1-4 stretch with only 2.8 runs per game highlights a scoring dip that sets the tone for this MLB prediction between the Padres and Giants. San Francisco has struggled over its last ten, but its 3.8 RPG in the most recent five contests signals a more stable offensive pulse than its opponent. With both sides trending below average totals, the sharper angle rests on trusting the Giants’ ability to squeeze out efficient run production while keeping the pace low.

Game Time

Starts in 10h 24m

Slated for Wednesday, August 20 at 09:40 PM ET inside Petco Park, conservative scoring is typical.

Odds & Spread Line

  • San Francisco Giants: +131
  • San Diego Padres: -147

Total: 8

  • Run Line — San Francisco Giants: +1.5 (-165)
  • Run Line — San Diego Padres: -1.5 (+140)

Latest Team Records

San Francisco Giants: 61-64 (Win %: 0.488)
San Diego Padres: 69-56 (Win %: 0.552)

Injury Report

Both teams are currently healthy with no major injury concerns.

Key Player Stats

San Francisco Giants

  • Rafael Devers: 0.257 AVG, 24 HR, 82 RBI
  • Heliot Ramos: 0.267 AVG, 15 HR, 53 RBI
  • Wilmer Flores: 0.248 AVG, 13 HR, 63 RBI

San Diego Padres

  • Manny Machado: 0.29 AVG, 20 HR, 72 RBI
  • Ramon Laureano: 0.295 AVG, 19 HR, 58 RBI
  • Ryan O’Hearn: 0.275 AVG, 15 HR, 50 RBI

Team Analysis

San Francisco Giants

The Giants’ 2-3 record in their last five games reflects a team still searching for rhythm but showing flashes of improved scoring with 3.8 RPG. That output is a step above their 2.4 RPG across the last ten, indicating that the offense is stabilizing. Rafael Devers’ run production continues to anchor the lineup, giving San Francisco a reliable bat to lean on in tight contests.

On the road, the Giants sit just under .500 with a 31-32 mark, proving they can compete away from home. Heliot Ramos adds balance with timely power, while Wilmer Flores provides depth in middle-order hitting. The combination of competent pitching and selective hitting makes San Francisco a live underdog in this spot despite recent struggles.

  • Batting Average: 0.232
  • Total Runs Scored: 510
  • Home Runs: 120
  • OBP: 0.309
  • SLG: 0.375
  • OPS: 0.683
  • ERA: 3.68
  • WHIP: 1.28

Away Record: 31-32 • Home Record: 30-33
Last 5 Games: 2-3 (3.8 RPG)
Last 10 Games: 2-8 (2.4 RPG)


San Diego Padres

The Padres’ 1-4 record over their last five outings with only 2.8 RPG signals a lineup that has cooled considerably. Manny Machado has kept producing, but the supporting cast has not delivered enough to sustain wins. This lack of consistency negates the benefit of their strong season record and forces them into low-scoring affairs.

Home form has been their biggest asset with a 39-21 record, yet Ramon Laureano and Ryan O’Hearn have not been able to spark the offense during this recent downturn. Even with pitching stability, San Diego Padres’ recent scoring slump leaves them vulnerable to a Giants team that is finding just enough offensive rhythm to exploit this dip. That makes the Padres less reliable as a favorite in this spot.

  • Batting Average: 0.251
  • Total Runs Scored: 523
  • Home Runs: 106
  • OBP: 0.322
  • SLG: 0.382
  • OPS: 0.704
  • ERA: 3.55
  • WHIP: 1.2

Away Record: 31-35 • Home Record: 39-21
Last 5 Games: 1-4 (2.8 RPG)
Last 10 Games: 6-4 (4.5 RPG)


Head-to-Head History

San Diego Padres lead 4–1 (Last 5 games)

  • August 19, 2025: SF 1 @ SD 5
  • August 18, 2025: SF 4 @ SD 3
  • August 13, 2025: SD 11 @ SF 1
  • August 12, 2025: SD 5 @ SF 1
  • August 11, 2025: SD 4 @ SF 1

Over/Under Trends

San Francisco Giants’ last 10 games have averaged 7.4 total runs, with 2 games that would have cleared today’s total of 8.

San Diego Padres’ last 10 games have averaged 7.3 combined runs, with 3 games clearing the same number of 8.

Moneyline Betting Prediction

The Giants hold value as the sharper side with a recent uptick to 3.8 RPG across the last five, contrasting with the Padres’ 2.8 RPG slump. San Francisco Giants’ road record shows they can compete in tough venues, while San Diego Padres’ recent offensive inconsistency negates their strong home mark. With Rafael Devers providing a steady anchor, the Giants are better positioned to grind out a narrow win.

Value-side alert: the San Francisco Giants at +131 profile as the play.

Over/Under Prediction

Last five form shows the San Diego Padres at 2.8 RPG and the San Francisco Giants at 3.8, giving context for the number.

These teams are combining for 6.6 runs per game recently — below the posted total of 8.0. That points toward the Under 8.0.

Bookmakers

You’ll find these markets at: FanDuel, BetOnline.ag, LowVig.ag, Caesars, Fanatics, MyBookie.ag, BetMGM, DraftKings, BetRivers, Bovada, BetUS.

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John Tamburino

John TamburinoVerified

Lead Analyst — data-first, former college baseball.

John Tamburino grew up on travel baseball and three years of varsity basketball, then played college baseball before shifting to analytics. He still watches everything—from weekday tennis to UFC—and will never forget the Diamondbacks’ 2001 run. At Parlamaz, John blends trusted data feeds with matchup context to find real value—no fluff, no paywalls.