Prediction Details

MLB Prediction: San Francisco Giants vs Los Angeles Dodgers (Saturday, September 20 at 09:10 PM ET)

Introduction

Updated

SF @ LADSF +198LAD -233O/U 8.5
Market / Trend SF LAD
Moneyline +198 -233
Total (O/U) 8.5
Run Line +1.5 (-111) -1.5 (-108)
Last 5 RPG 3.0 4.8
Record 76–77 86–67
Lines: BetMGM, BetOnline.ag, BetRivers, BetUS +7 more

More MLB picks: San Francisco Giants · Los Angeles Dodgers

Los Angeles enters this matchup analysis with a commanding home record of 51-28, while San Francisco has stumbled through a 1-4 stretch across its last five. The Dodgers’ steady 7-3 mark in their last 10 contrasts sharply with the Giants’ 3-7 skid, signaling a clear gap in form. With the Giants averaging just 3.0 runs per game in their recent five, and the Dodgers controlling the head-to-head series, this MLB prediction leans firmly toward Los Angeles asserting control behind its consistent lineup.

Game Time

Starts in 19h 2m

Scheduled for Saturday, September 20 at 09:10 PM ET inside Dodger Stadium, totals often track with starting pitching.

Odds & Spread Line

  • San Francisco Giants: +198
  • Los Angeles Dodgers: -233

Total: 8.5

  • Run Line — San Francisco Giants: +1.5 (-111)
  • Run Line — Los Angeles Dodgers: -1.5 (-108)

Latest Team Records

San Francisco Giants: 76-77 (Win %: 0.497)
Los Angeles Dodgers: 86-67 (Win %: 0.562)

Injury Report

San Francisco Giants are missing Dominic Smith (Hamstring), listed as 10-Day-IL; Carson Whisenhunt (Back), listed as 15-Day-IL.

Los Angeles Dodgers are missing Brock Stewart (Shoulder), listed as 15-Day-IL.

Key Player Stats

San Francisco Giants

  • Rafael Devers: 0.253 AVG, 31 HR, 104 RBI
  • Willy Adames: 0.226 AVG, 28 HR, 82 RBI
  • Heliot Ramos: 0.257 AVG, 17 HR, 61 RBI

Los Angeles Dodgers

  • Shohei Ohtani: 0.283 AVG, 51 HR, 95 RBI
  • Freddie Freeman: 0.295 AVG, 21 HR, 84 RBI
  • Andy Pages: 0.277 AVG, 25 HR, 81 RBI

Team Analysis

San Francisco Giants

The Giants’ 1-4 record across their last five games highlights a team stuck in a slump, with offensive production capped at just 3.0 runs per game. On the road, their 38-41 mark reinforces the lack of consistency when removed from home conditions. Rafael Devers has provided some power, but his efforts have not been enough to offset the team’s broader scoring struggles.

Willy Adames has flashed occasional run production, yet the lineup as a whole has not kept pace with stronger National League opponents. Heliot Ramos adds depth, but the recent 3-7 stretch across the last 10 games drives home how unreliable the offense has been. With scoring inconsistency and road form working against them, San Francisco carries little betting appeal in this spot.

  • Batting Average: 0.235
  • Total Runs Scored: 663
  • Home Runs: 162
  • OBP: 0.311
  • SLG: 0.385
  • OPS: 0.696
  • ERA: 3.83
  • WHIP: 1.3

Away Record: 38-41 • Home Record: 38-37
Last 5 Games: 1-4 (3.0 RPG)
Last 10 Games: 3-7 (3.7 RPG)


Los Angeles Dodgers

The Dodgers’ 3-2 record in their last five games, with 4.8 runs per game, reflects a steady offensive rhythm backed by a dominant 51-28 home record. Shohei Ohtani’s elite power presence forces opposing pitchers into mistakes, creating scoring opportunities even when the lineup doesn’t fully click. Their 7-3 mark across the last 10 solidifies confidence in their ability to handle divisional opponents like San Francisco.

Freddie Freeman has delivered consistent contact and run support, while Andy Pages has added valuable middle-order production to keep pressure on opposing pitching. The Dodgers’ overall 780 runs scored this season emphasize depth and reliability, particularly at home where their offense perks up. With both form and venue advantage aligning, Los Angeles projects as the dominant side here.

  • Batting Average: 0.254
  • Total Runs Scored: 780
  • Home Runs: 225
  • OBP: 0.329
  • SLG: 0.439
  • OPS: 0.768
  • ERA: 4.03
  • WHIP: 1.26

Away Record: 36-39 • Home Record: 51-28
Last 5 Games: 3-2 (4.8 RPG)
Last 10 Games: 7-3 (6.4 RPG)


Head-to-Head History

Los Angeles Dodgers lead 6–2 (Last 8 games)

  • September 19, 2025: SF 3 @ LAD 6
  • September 18, 2025: SF 1 @ LAD 2
  • September 14, 2025: LAD 10 @ SF 2
  • September 13, 2025: LAD 13 @ SF 7
  • September 12, 2025: LAD 1 @ SF 5
  • July 13, 2025: LAD 5 @ SF 2
  • July 12, 2025: LAD 2 @ SF 1
  • July 11, 2025: LAD 7 @ SF 8

Over/Under Trends

San Francisco Giants’ last 10 games have averaged 9.2 total runs, with 5 games that would have cleared today’s total of 8.5.

Los Angeles Dodgers’ last 10 games have averaged 9.9 combined runs, with 7 games clearing the same number of 8.5.

Moneyline Betting Prediction

The Dodgers’ combination of a 51-28 home record, a 7-3 stretch over their last 10 games, and a commanding 6-2 lead in the season series against San Francisco makes them the clear side. With Ohtani, Freeman, and Pages driving consistent run production, Los Angeles holds every statistical edge necessary to secure another victory.

This sets up cleanly for the Los Angeles Dodgers to finish on top.

Over/Under Prediction

Recent five-game scoring: the Los Angeles Dodgers are at 4.8 RPG and the San Francisco Giants at 3.0 — a useful baseline against the total.

These teams are combining for 7.8 runs per game recently — below the posted total of 8.5. That points toward the Under 8.5.

Bookmakers

Odds courtesy of: BetOnline.ag, LowVig.ag, Caesars, DraftKings.

Parlamaz may earn affiliate commissions from links in this article.

MLB Predictions FAQ

How should I size my bets?

Use a consistent unit (about 1–2% of bankroll). Singles should be most of your volume. We like parlays—smart ones. Keep legs tight (2–3), cap risk to 0.25–0.5u, and pass when the price isn’t there.

How often are picks updated?

Daily. We update for confirmed lineups, injuries, and market moves. Check back near first pitch for final notes.

John Tamburino

John TamburinoVerified

Lead Analyst — data-first, former college baseball.

John Tamburino grew up on travel baseball and three years of varsity basketball, then played college baseball before shifting to analytics. He still watches everything—from weekday tennis to all major league sports—and will never forget the Diamondbacks’ World Series run. At Parlamaz, John blends trusted data feeds with matchup context to find real value—no fluff, no paywalls.