Prediction Details

MLB Prediction: San Francisco Giants vs Los Angeles Dodgers (Friday, September 19 at 10:10 PM ET)

Introduction

Updated

SF @ LADSF +145LAD -175O/U 8.5
Market / Trend SF LAD
Moneyline +145 -175
Total (O/U) 8.5
Run Line +1.5 (-150) -1.5 (126)
Last 5 RPG 2.8 5.6
Record 76–76 85–67
Lines: BetMGM, BetOnline.ag, BetRivers, BetUS +7 more

More MLB picks: San Francisco Giants · Los Angeles Dodgers

The Dodgers have taken six of the last eight meetings against the Giants, including a tight 2-1 result in their most recent contest, and that dominance frames this MLB prediction. San Francisco has dropped four of its last five with just 2.8 runs per game in that span, while Los Angeles continues to produce steady offense at over five runs per game. With the Giants fading on the road and the Dodgers asserting control in this matchup, the betting edge is clear.

Game Time

Starts in 20h 4m

Taking place at Friday, September 19 at 10:10 PM ET at Dodger Stadium, a balanced venue where matchups drive scoring.

Odds & Spread Line

  • San Francisco Giants: +145
  • Los Angeles Dodgers: -175

Total: 8.5

  • Run Line — San Francisco Giants: +1.5 (-150)
  • Run Line — Los Angeles Dodgers: -1.5 (+126)

Latest Team Records

San Francisco Giants: 76-76 (Win %: 0.5)
Los Angeles Dodgers: 85-67 (Win %: 0.559)

Injury Report

The San Francisco Giants are currently healthy with no major injury concerns.

Los Angeles Dodgers are missing Tony Gonsolin (Elbow), listed as 60-Day-IL.

Key Player Stats

San Francisco Giants

  • Rafael Devers: 0.254 AVG, 31 HR, 103 RBI
  • Willy Adames: 0.227 AVG, 28 HR, 82 RBI
  • Heliot Ramos: 0.259 AVG, 17 HR, 61 RBI

Los Angeles Dodgers

  • Shohei Ohtani: 0.282 AVG, 51 HR, 95 RBI
  • Freddie Freeman: 0.295 AVG, 21 HR, 83 RBI
  • Andy Pages: 0.278 AVG, 25 HR, 81 RBI

Team Analysis

San Francisco Giants

The Giants enter this contest on a 1-4 stretch in their last five, averaging only 2.8 runs per game, which signals a clear offensive slump. Rafael Devers has been the most reliable run producer, but the team’s inability to string together consistent at-bats has left them vulnerable in close contests. On the road, their losing record shows that they have struggled to sustain pressure away from home, particularly against higher-caliber opponents.

Willy Adames and Heliot Ramos have contributed power, but the lack of timely hitting makes it difficult for the Giants to capitalize on those moments. Their 4-6 mark over the last 10 games reflects inconsistency, with only sporadic offensive bursts keeping them competitive. Against a Dodgers team that has dominated recent head-to-head meetings, San Francisco Giants’ form does not inspire confidence for bettors looking at the moneyline.

  • Batting Average: 0.236
  • Total Runs Scored: 662
  • Home Runs: 162
  • OBP: 0.311
  • SLG: 0.387
  • OPS: 0.698
  • ERA: 3.84
  • WHIP: 1.31

Away Record: 38-40 • Home Record: 38-37
Last 5 Games: 1-4 (2.8 RPG)
Last 10 Games: 4-6 (4.5 RPG)


Los Angeles Dodgers

The Dodgers’ 3-2 record in their last five and 7-3 over their last 10 emphasizes steady performance, with 5.6 runs per game in the most recent stretch. Shohei Ohtani’s power threat combined with Freddie Freeman’s consistency has kept the lineup balanced and difficult to pitch against. At home, their 50-28 record highlights a clear situational advantage that consistently translates into wins.

Andy Pages adds depth to the Dodgers’ order, ensuring that opposing pitchers cannot simply work around the top of the lineup. Their recent scoring profile shows they are capable of producing runs in multiple ways, making them more reliable than the Giants in close totals markets. With their superior home dominance and proven head-to-head control, the Dodgers enter this matchup as the more stable and confident side.

  • Batting Average: 0.254
  • Total Runs Scored: 778
  • Home Runs: 225
  • OBP: 0.33
  • SLG: 0.44
  • OPS: 0.77
  • ERA: 4.05
  • WHIP: 1.27

Away Record: 36-39 • Home Record: 50-28
Last 5 Games: 3-2 (5.6 RPG)
Last 10 Games: 7-3 (6.1 RPG)


Head-to-Head History

Los Angeles Dodgers lead 6–2 (Last 8 games)

  • September 18, 2025: SF 1 @ LAD 2
  • September 14, 2025: LAD 10 @ SF 2
  • September 13, 2025: LAD 13 @ SF 7
  • September 12, 2025: LAD 1 @ SF 5
  • July 13, 2025: LAD 5 @ SF 2
  • July 12, 2025: LAD 2 @ SF 1
  • July 11, 2025: LAD 7 @ SF 8
  • June 15, 2025: SF 4 @ LAD 5

Over/Under Trends

San Francisco Giants’ last 10 games have averaged 9.9 total runs, with 5 games that would have cleared today’s total of 8.5.

Los Angeles Dodgers’ last 10 games have averaged 9.4 combined runs, with 6 games clearing the same number of 8.5.

Moneyline Betting Prediction

The Dodgers’ strong home record, combined with a 7-3 run across their last 10 and clear head-to-head dominance, makes them the definitive side here. With Ohtani, Freeman, and Pages anchoring a consistent lineup against a Giants squad struggling to generate offense, the momentum and situational splits point squarely toward Los Angeles.

Data supports the Los Angeles Dodgers as the right side.

Over/Under Prediction

In their last five, the Los Angeles Dodgers have produced 5.6 RPG and the San Francisco Giants 2.8. That output frames how this total sets up.

These teams are combining for 8.4 runs per game recently — right around the posted total of 8.5. That points toward the Under 8.5.

Bookmakers

Lines retrieved from: FanDuel, MyBookie.ag, LowVig.ag, BetOnline.ag, Caesars, DraftKings, BetMGM, BetUS, Bovada, BetRivers, Fanatics.

Parlamaz earns affiliate commissions from links.

MLB Predictions FAQ

What do moneyline, run line, and total mean?

Moneyline is who wins the game. Run line is a spread, usually ±1.5 runs. The total (over/under) is combined runs by both teams.

How should I size my bets?

Use a consistent unit (about 1–2% of bankroll). Singles should be most of your volume. We like parlays—smart ones. Keep legs tight (2–3), cap risk to 0.25–0.5u, and pass when the price isn’t there.

John Tamburino

John TamburinoVerified

Lead Analyst — data-first, former college baseball.

John Tamburino grew up on travel baseball and three years of varsity basketball, then played college baseball before shifting to analytics. He still watches everything—from weekday tennis to all major league sports—and will never forget the Diamondbacks’ World Series run. At Parlamaz, John blends trusted data feeds with matchup context to find real value—no fluff, no paywalls.