- August 21, 2025
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MLB Prediction: Los Angeles Dodgers vs San Diego Padres (Friday, August 22 at 09:40 PM ET)
Introduction
Market / Trend | LAD | SD |
---|---|---|
Moneyline | -125 | +105 |
Total (O/U) | 8.0 | |
Run Line | -1.5 (140) | +1.5 (-165) |
Last 5 RPG | 6.2 | 5.6 |
Record | 72–55 | 71–56 |
Lines: BetMGM, BetOnline.ag, BetRivers, BetUS +7 more |
More MLB picks: Los Angeles Dodgers · San Diego Padres
Los Angeles enters this matchup analysis with a 3-2 record across its last five games, averaging 6.2 runs per contest, while San Diego has matched that 3-2 mark with 5.6 runs per game. The Dodgers’ ability to consistently generate offense against this opponent, combined with their 4–1 head-to-head edge in the last five meetings, sets the tone for a confident MLB prediction. With both lineups producing above five runs per game recently, the scoring profile leans heavily toward an Over result, and the Dodgers’ sharper form makes them the side to back.
Game Time
Taking place at Friday, August 22 at 09:40 PM ET inside Petco Park, conservative scoring is typical.
Odds & Spread Line
- Los Angeles Dodgers: -125
- San Diego Padres: +105
Total: 8
- Run Line — Los Angeles Dodgers: -1.5 (+140)
- Run Line — San Diego Padres: +1.5 (-165)
Latest Team Records
Los Angeles Dodgers: 72-55 (Win %: 0.567)
San Diego Padres: 71-56 (Win %: 0.559)
Injury Report
Los Angeles Dodgers are missing Roki Sasaki (Shoulder), listed as 60-Day-IL.
The San Diego Padres are currently healthy with no major injury concerns.
Key Player Stats
Los Angeles Dodgers
- Shohei Ohtani: 0.285 AVG, 44 HR, 83 RBI
- Freddie Freeman: 0.302 AVG, 15 HR, 70 RBI
- Andy Pages: 0.272 AVG, 20 HR, 70 RBI
San Diego Padres
- Manny Machado: 0.292 AVG, 21 HR, 74 RBI
- Ramon Laureano: 0.297 AVG, 19 HR, 58 RBI
- Ryan O’Hearn: 0.28 AVG, 16 HR, 53 RBI
Team Analysis
Los Angeles Dodgers
The Dodgers sit at 72-55, reflecting steady performance across the season and a balanced scoring rhythm. Their recent 3-2 stretch with 6.2 runs per game signals reliability at the plate, and the 5-5 mark in the last 10 shows they have maintained competitive output despite mixed results. Shohei Ohtani’s power presence has been a consistent driver, and his production ensures Los Angeles has a reliable offensive core when games tighten.
On the road, the Dodgers have managed a 32-31 record, showing resilience away from home while keeping run production steady. Freddie Freeman’s ability to sustain long innings and Andy Pages’ added pop in the order give this lineup depth that travels well. With scoring consistency above six runs per game recently, Los Angeles projects as the stronger offensive side in this matchup.
- Batting Average: 0.254
- Total Runs Scored: 657
- Home Runs: 188
- OBP: 0.331
- SLG: 0.44
- OPS: 0.77
- ERA: 4.15
- WHIP: 1.31
Away Record: 32-31 • Home Record: 41-24
Last 5 Games: 3-2 (6.2 RPG)
Last 10 Games: 5-5 (5.5 RPG)
San Diego Padres
The Padres hold a 71-56 record, keeping pace in the standings with a strong 41-21 home mark. Their last five games have produced a 3-2 record with 5.6 runs per game, showing they are capable of keeping contests competitive but not consistently dominating. Manny Machado has been central to their run production, yet the team has lacked the same late-game finishing edge as their opponent.
Across the last 10 games, San Diego is 6-4 with 5.0 runs per game, proving steady but not explosive. Ramon Laureano’s recent production helps keep them afloat offensively, while Ryan O’Hearn adds balance to the middle of the order. Despite the strong home record, the Padres’ inability to consistently outpace the Dodgers in recent head-to-head meetings keeps them a step behind in betting value.
- Batting Average: 0.251
- Total Runs Scored: 531
- Home Runs: 110
- OBP: 0.322
- SLG: 0.385
- OPS: 0.707
- ERA: 3.53
- WHIP: 1.2
Away Record: 31-35 • Home Record: 41-21
Last 5 Games: 3-2 (5.6 RPG)
Last 10 Games: 6-4 (5.0 RPG)
Head-to-Head History
Los Angeles Dodgers lead 4–1 (Last 5 games)
- August 17, 2025: SD 4 @ LAD 5
- August 16, 2025: SD 0 @ LAD 6
- August 15, 2025: SD 2 @ LAD 3
- June 19, 2025: SD 5 @ LAD 3
- June 18, 2025: SD 3 @ LAD 4
Over/Under Trends
Los Angeles Dodgers’ last 10 games have averaged 10.2 total runs, with 7 games that would have cleared today’s total of 8.
San Diego Padres’ last 10 games have averaged 7.7 combined runs, with 4 games clearing the same number of 8.
Moneyline Betting Prediction
The Dodgers’ superior scoring pace, road resilience, and 4–1 head-to-head dominance establish them as the more reliable side. With Ohtani’s power anchoring the order and Freeman and Pages adding depth, Los Angeles holds a decisive offensive edge. The Padres’ steady but unspectacular home production is not enough to offset the Dodgers’ proven ability to close games, making Los Angeles the clear moneyline pick.
The Los Angeles Dodgers are the sharp side on form and splits.
Over/Under Prediction
Recent five-game scoring: the San Diego Padres are at 5.6 RPG and the Los Angeles Dodgers at 6.2 — a useful baseline against the total.
These teams are combining for 11.8 runs per game recently — above the posted total of 8.0. That points toward the Over 8.0.
Bookmakers
Find these odds at: FanDuel, MyBookie.ag, LowVig.ag, BetOnline.ag, Caesars, DraftKings, Bovada, BetUS, BetMGM, BetRivers, Fanatics.
Parlamaz may earn affiliate commissions from links in this article.
MLB Predictions FAQ
How does Parlamaz make Los Angeles Dodgers vs San Diego Padres MLB predictions?
We use trusted data feeds and real-time odds to model each matchup. We weight the numbers that move lines—team form, matchup history, injuries, park factors, totals trends, and betting momentum—then compare our price to the market to find value. All signal, no noise. No paywalls.
What’s a good price range for today’s pick (Aug 22, 2025)?
We list a target price in the post. If the market moves past that number, reduce stake size or pass instead of chasing worse odds.
What do moneyline, run line, and total mean?
Moneyline is who wins the game. Run line is a spread, usually ±1.5 runs. The total (over/under) is combined runs by both teams.

John TamburinoVerified
Lead Analyst — data-first, former college baseball.
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