MLB Prediction: Arizona Diamondbacks vs Minnesota Twins (Friday, September 12 at 08:10 PM ET)
Introduction
| Market / Trend | ARI | MIN |
|---|---|---|
| Moneyline | +120 | -145 |
| Total (O/U) | 8.0 | |
| Run Line | +1.5 (-178) | -1.5 (152) |
| Last 5 RPG | 4.4 | 4.8 |
| Record | 73–74 | 64–82 |
| Lines: BetMGM, BetOnline.ag, BetRivers, BetUS +7 more | ||
More MLB picks: Arizona Diamondbacks · Minnesota Twins
Arizona enters this interleague matchup analysis against Minnesota with a 5-5 mark across the last 10 games, producing 4.8 runs per contest, while the Twins have stumbled to 2-8 in the same span. That contrast in rhythm sets up a clear betting preview: the Diamondbacks’ steadier scoring and deeper lineup balance outweigh the Twins’ recent inconsistency. With both clubs averaging above four runs per game, the offensive environment leans toward a high-scoring outcome, making this an attractive MLB prediction for bettors targeting both the side and total.
Game Time
Game time: Friday, September 12 at 08:10 PM ET at Target Field, cooler evening air keeps scoring modest.
Odds & Spread Line
- Arizona Diamondbacks: +120
- Minnesota Twins: -145
Total: 8
- Run Line — Arizona Diamondbacks: +1.5 (-178)
- Run Line — Minnesota Twins: -1.5 (+152)
Latest Team Records
Arizona Diamondbacks: 73-74 (Win %: 0.497)
Minnesota Twins: 64-82 (Win %: 0.438)
Injury Report
Arizona Diamondbacks are missing Ketel Marte (Foot), listed as Day-To-Day; Tyler Locklear (Elbow), listed as 10-Day-IL; Lourdes Gurriel Jr. (Knee), listed as 10-Day-IL. No other significant injuries are reported.
Minnesota Twins are missing David Festa (Shoulder), listed as 15-Day-IL.
Key Player Stats
Arizona Diamondbacks
- Geraldo Perdomo: 0.284 AVG, 18 HR, 93 RBI
- Corbin Carroll: 0.254 AVG, 30 HR, 74 RBI
- Ketel Marte: 0.281 AVG, 25 HR, 65 RBI
Minnesota Twins
- Byron Buxton: 0.275 AVG, 31 HR, 76 RBI
- Trevor Larnach: 0.256 AVG, 16 HR, 57 RBI
- Brooks Lee: 0.238 AVG, 14 HR, 57 RBI
Team Analysis
Arizona Diamondbacks
The Diamondbacks’ 2-3 record over their last five games reflects a team that has been competitive but not fully clicking, yet their 4.4 runs per game in that stretch shows the offense remains active. Geraldo Perdomo has provided stability in the lineup, while Corbin Carroll’s power threat keeps pitchers on edge. With a 35-40 road record, the Diamondbacks have proven capable of producing runs away from home, making them a dangerous underdog in this setting.
Over the last 10 contests, Arizona sits at 5-5 with 4.8 runs per game, a sign of steady offensive output despite mixed results. Ketel Marte, even while managing injury status, continues to be a central figure when in the lineup, and his impact extends to the team’s confidence at the plate. Given the Twins’ struggles, Arizona Diamondbacks’ balanced production and offensive depth give them a clear path to control this matchup.
- Batting Average: 0.25
- Total Runs Scored: 724
- Home Runs: 199
- OBP: 0.323
- SLG: 0.434
- OPS: 0.757
- ERA: 4.47
- WHIP: 1.32
Away Record: 35-40 • Home Record: 38-34
Last 5 Games: 2-3 (4.4 RPG)
Last 10 Games: 5-5 (4.8 RPG)
Minnesota Twins
The Twins have dropped eight of their last ten contests, averaging 4.4 runs per game, and that extended slump highlights their lack of consistency. Byron Buxton remains the primary offensive driver, but his production has not been enough to lift the team through this skid. A 35-36 home record highlights their mediocrity at Target Field, where they have failed to establish any real edge this season.
In the past five games, Minnesota has gone 2-3 while scoring 4.8 runs per contest, showing flashes of offense but lacking the finishing ability to convert into wins. Trevor Larnach and Brooks Lee have delivered occasional contributions, but the lineup has struggled to string together rallies consistently. Against a Diamondbacks team with steadier form, the Twins’ inability to capitalize on home field makes them vulnerable in this spot.
- Batting Average: 0.239
- Total Runs Scored: 617
- Home Runs: 173
- OBP: 0.312
- SLG: 0.398
- OPS: 0.71
- ERA: 4.6
- WHIP: 1.33
Away Record: 29-46 • Home Record: 35-36
Last 5 Games: 2-3 (4.8 RPG)
Last 10 Games: 2-8 (4.4 RPG)
Head-to-Head History
No recent matchups between these teams in 2025.
Over/Under Trends
Arizona Diamondbacks’ last 10 games have averaged 9.5 total runs, with 5 games that would have cleared today’s total of 8.
Minnesota Twins’ last 10 games have averaged 11.0 combined runs, with 6 games clearing the same number of 8.
Moneyline Betting Prediction
The Diamondbacks’ steadier 5-5 stretch across their last 10 games, combined with stronger road scoring balance, positions them as the more reliable side against a Twins team mired in a 2-8 slump. With Perdomo and Carroll anchoring an offense that continues to produce above four runs a game, Arizona carries the sharper form and matchup edge to secure this interleague victory.
The Arizona Diamondbacks at +120 check enough boxes to be the value side.
Over/Under Prediction
Last five form shows the Minnesota Twins at 4.8 RPG and the Arizona Diamondbacks at 4.4, giving context for the number.
These teams are combining for 9.2 runs per game recently — above the posted total of 8.0. That points toward the Over 8.0.
Bookmakers
Lines retrieved from: FanDuel, BetOnline.ag, LowVig.ag, Caesars, DraftKings, MyBookie.ag, BetUS, Bovada, BetRivers, BetMGM, Fanatics.
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MLB Predictions FAQ
What’s a good price range for today’s pick (Sep 12, 2025)?
We list a target price in the post. If the market moves past that number, reduce stake size or pass instead of chasing worse odds.
How should I size my bets?
Use a consistent unit (about 1–2% of bankroll). Singles should be most of your volume. We like parlays—smart ones. Keep legs tight (2–3), cap risk to 0.25–0.5u, and pass when the price isn’t there.
