Prediction Details

MLB Prediction: Houston Astros vs Toronto Blue Jays (Wednesday, September 10 at 07:05 PM ET)

Introduction

Updated

HOU @ TORHOU +129TOR -143O/U 9.0
Market / Trend HOU TOR
Moneyline +129 -143
Total (O/U) 9.0
Run Line +1.5 (-170) -1.5 (145)
Last 5 RPG 4.6 5.6
Record 78–67 83–61
Lines: BetMGM, BetOnline.ag, BetRivers, BetUS +7 more

More MLB picks: Houston Astros · Toronto Blue Jays

Toronto has gone 3-2 in its last five games with 5.6 runs per game, while Houston has dropped four of five but still averaged 4.6 runs in that stretch. This matchup analysis shows a clear betting edge: the Astros’ lineup remains dangerous even in a slump, and their recent head-to-head success against Toronto signals value. With both teams combining for over 10 runs per game recently, this MLB prediction leans firmly toward Houston on the moneyline and a high-scoring outcome.

Game Time

Starts in 9h 14m

Game time: Wednesday, September 10 at 07:05 PM ET under the roof at Rogers Centre, pace quickens on turf.

Odds & Spread Line

  • Houston Astros: +129
  • Toronto Blue Jays: -143

Total: 9

  • Run Line — Houston Astros: +1.5 (-170)
  • Run Line — Toronto Blue Jays: -1.5 (+145)

Latest Team Records

Houston Astros: 78-67 (Win %: 0.538)
Toronto Blue Jays: 83-61 (Win %: 0.576)

Injury Report

Houston Astros are missing Isaac Paredes (Hamstring), listed as 60-Day-IL; Brendan Rodgers (Back), listed as 60-Day-IL; Pedro Leon (Knee), listed as 60-Day-IL; Josh Hader (Shoulder), listed as 15-Day-IL. No other significant injuries are reported.

The Toronto Blue Jays are currently healthy with no major injury concerns.

Key Player Stats

Houston Astros

  • Jose Altuve: 0.263 AVG, 24 HR, 69 RBI
  • Jeremy Pena: 0.303 AVG, 15 HR, 54 RBI
  • Christian Walker: 0.234 AVG, 22 HR, 76 RBI

Toronto Blue Jays

  • Bo Bichette: 0.311 AVG, 18 HR, 93 RBI
  • George Springer: 0.3 AVG, 28 HR, 73 RBI
  • Vladimir Guerrero Jr.: 0.304 AVG, 23 HR, 79 RBI

Team Analysis

Houston Astros

The Astros enter this contest off a 1-4 stretch in their last five games, averaging 4.6 runs per outing. While the results show recent struggles, the offense has not gone silent, maintaining steady production anchored by Jose Altuve and Jeremy Pena. Their road record of 35-35 demonstrates resilience, and with Christian Walker adding power, the lineup still projects value against a Toronto staff that has been hittable.

Over the last 10 games, Houston has gone 3-7 with 4.1 runs per game, signaling inconsistency but not collapse. The ability to generate runs despite losses reflects a lineup more dangerous than the record suggests, making them a live underdog. With proven success against Toronto earlier in the season, the Astros’ offensive profile is positioned to break through again.

  • Batting Average: 0.253
  • Total Runs Scored: 612
  • Home Runs: 160
  • OBP: 0.318
  • SLG: 0.401
  • OPS: 0.72
  • ERA: 3.85
  • WHIP: 1.22

Away Record: 35-35 • Home Record: 43-32
Last 5 Games: 1-4 (4.6 RPG)
Last 10 Games: 3-7 (4.1 RPG)


Toronto Blue Jays

The Blue Jays hold an impressive 46-24 home record, and their offense has been consistent at Rogers Centre. They have won three of their last five games, averaging 5.6 runs per contest, with Bo Bichette driving the middle of the order. George Springer has also provided steady power, giving Toronto a balanced attack at home.

Over the last 10 games, Toronto has been even at 5-5, averaging 5.5 runs, showing steady but not dominant form. Vladimir Guerrero Jr. continues to be a force in the lineup, but the team’s pitching has allowed opponents to stay competitive. Despite their home-field edge, the Blue Jays’ recent inconsistency opens the door for a sharp underdog like Houston to capitalize.

  • Batting Average: 0.269
  • Total Runs Scored: 719
  • Home Runs: 175
  • OBP: 0.338
  • SLG: 0.432
  • OPS: 0.77
  • ERA: 4.23
  • WHIP: 1.27

Away Record: 37-37 • Home Record: 46-24
Last 5 Games: 3-2 (5.6 RPG)
Last 10 Games: 5-5 (5.5 RPG)


Head-to-Head History

Houston Astros lead 3–1 (Last 4 games)

  • September 09, 2025: HOU 3 @ TOR 4
  • April 23, 2025: TOR 1 @ HOU 3
  • April 22, 2025: TOR 1 @ HOU 5
  • April 21, 2025: TOR 0 @ HOU 7

Over/Under Trends

Houston Astros’ last 10 games have averaged 8.5 total runs, with 4 games that would have cleared today’s total of 9.

Toronto Blue Jays’ last 10 games have averaged 10.4 combined runs, with 3 games clearing the same number of 9.

Moneyline Betting Prediction

Despite a 1-4 stretch, Houston Astros’ lineup has consistently produced runs, and their prior 3-1 head-to-head edge over Toronto highlights matchup value. With Altuve and Pena providing on-base pressure and Walker’s power threat, the Astros’ offense aligns well against a Blue Jays staff that has allowed opponents to stay in games, making Houston the sharper moneyline side.

Mismatch vs perception: the Houston Astros at +129 are the sharper angle.

Over/Under Prediction

In their last five, the Toronto Blue Jays have produced 5.6 RPG and the Houston Astros 4.6. That output frames how this total sets up.

These teams are combining for 10.2 runs per game recently — above the posted total of 9.0. That points toward the Over 9.0.

Bookmakers

MLB Lines retrieved from: FanDuel, BetRivers, MyBookie.ag, Fanatics, DraftKings, Caesars, BetMGM, BetOnline.ag, LowVig.ag, Bovada, BetUS.

Parlamaz may earn affiliate commissions from links in this article.

MLB Predictions FAQ

What’s a good price range for today’s pick (Sep 10, 2025)?

We list a target price in the post. If the market moves past that number, reduce stake size or pass instead of chasing worse odds.

What do moneyline, run line, and total mean?

Moneyline is who wins the game. Run line is a spread, usually ±1.5 runs. The total (over/under) is combined runs by both teams.

How does Parlamaz make Houston Astros vs Toronto Blue Jays MLB predictions?

We use trusted data feeds and real-time odds to model each matchup. We weight the numbers that move lines—team form, matchup history, injuries, park factors, totals trends, and betting momentum—then compare our price to the market to find value. All signal, no noise. No paywalls.

John Tamburino

John TamburinoVerified

Lead Analyst — data-first, former college baseball.

John Tamburino grew up on travel baseball and three years of varsity basketball, then played college baseball before shifting to analytics. He still watches everything—from weekday tennis to all major league sports—and will never forget the Diamondbacks’ World Series run. At Parlamaz, John blends trusted data feeds with matchup context to find real value—no fluff, no paywalls.