Prediction Details

MLB Prediction: Los Angeles Dodgers vs Arizona Diamondbacks (Thursday, September 25 at 03:40 PM ET)

Introduction

Updated

LAD @ ARILAD -149ARI +134O/U 8.5
Market / Trend LAD ARI
Moneyline -149 +134
Total (O/U) 8.5
Run Line -1.5 (-105) +1.5 (-114)
Last 5 RPG 4.6 4.8
Record 88–69 80–77
Lines: BetMGM, BetOnline.ag, BetRivers, BetUS +7 more

More MLB picks: Los Angeles Dodgers · Arizona Diamondbacks

The Dodgers enter this matchup analysis with steadier form, winning 6 of their last 10 while averaging 5.1 runs per game, signaling offensive balance heading into Arizona. The Diamondbacks have been productive as well, but Los Angeles’ ability to sustain scoring across multiple bats creates a sharper edge. With both clubs clearing 8.5 runs in 7 of their last 10, the total leans high, and the Dodgers’ consistency positions them as the superior moneyline side.

Game Time

Starts in 6h 54m

Slated for Thursday, September 25 at 03:40 PM ET inside Chase Field, roof conditions stabilize totals.

Odds & Spread Line

  • Los Angeles Dodgers: -149
  • Arizona Diamondbacks: +134

Total: 8.5

  • Run Line — Los Angeles Dodgers: -1.5 (-105)
  • Run Line — Arizona Diamondbacks: +1.5 (-114)

Latest Team Records

Los Angeles Dodgers: 88-69 (Win %: 0.561)
Arizona Diamondbacks: 80-77 (Win %: 0.51)

Injury Report

Los Angeles Dodgers are missing Brock Stewart (Shoulder), listed as 15-Day-IL; Will Smith (Hand), listed as 10-Day-IL; Michael Kopech (Knee), listed as 15-Day-IL; Tony Gonsolin (Elbow), listed as 60-Day-IL. No other significant injuries are reported.

Arizona Diamondbacks are missing Juan Burgos (Forearm), listed as 15-Day-IL; Lourdes Gurriel Jr. (Knee), listed as 10-Day-IL.

Key Player Stats

Los Angeles Dodgers

  • Shohei Ohtani: 0.282 AVG, 53 HR, 99 RBI
  • Freddie Freeman: 0.292 AVG, 21 HR, 85 RBI
  • Andy Pages: 0.277 AVG, 25 HR, 82 RBI

Arizona Diamondbacks

  • Geraldo Perdomo: 0.291 AVG, 19 HR, 98 RBI
  • Corbin Carroll: 0.26 AVG, 31 HR, 83 RBI
  • Ketel Marte: 0.28 AVG, 26 HR, 70 RBI

Team Analysis

Los Angeles Dodgers

The Dodgers’ 3-2 mark across their last five games reflects a team capable of responding to close contests, with a steady 4.6 runs per game over that span. On the road, they have faced challenges with a sub-.500 record, but their offensive stability, led by Shohei Ohtani’s power production, keeps them competitive in hostile environments. This ability to consistently generate runs on the road is a critical betting edge against Arizona Diamondbacks’ pitching profile.

Across their last 10 games, Los Angeles has gone 6-4 with 5.1 runs per game, underscoring a healthy offensive rhythm. Freddie Freeman’s situational hitting reinforces the lineup’s depth, while Andy Pages adds additional run support that prevents extended scoring droughts. When combining this form with their season-long run production, the Dodgers project as the more reliable side to back.

  • Batting Average: 0.253
  • Total Runs Scored: 803
  • Home Runs: 235
  • OBP: 0.328
  • SLG: 0.44
  • OPS: 0.768
  • ERA: 4.02
  • WHIP: 1.26

Away Record: 37-40 • Home Record: 52-29
Last 5 Games: 3-2 (4.6 RPG)
Last 10 Games: 6-4 (5.1 RPG)


Arizona Diamondbacks

Arizona Diamondbacks’ 3-2 record in their last five contests shows competitiveness, with 4.8 runs per game keeping them in scoring range. Geraldo Perdomo’s production in run creation has been pivotal, giving the Diamondbacks a steady bat at the top of their order. Their 43-37 home record reflects an ability to capitalize on familiar conditions, but their pitching staff has struggled to suppress higher-tier offenses like Los Angeles.

Over the last 10 games, Arizona Diamondbacks’ 7-3 record with 5.0 runs per game highlights recent efficiency, though their success has leaned heavily on timely hitting from Corbin Carroll and Ketel Marte. That reliance on clustered production leaves them vulnerable when facing deeper lineups, especially against teams like Los Angeles that can spread scoring threats across multiple hitters. While competitive at home, the Diamondbacks lack the consistent offensive ceiling to outpace the Dodgers across nine innings.

  • Batting Average: 0.252
  • Total Runs Scored: 782
  • Home Runs: 210
  • OBP: 0.325
  • SLG: 0.434
  • OPS: 0.759
  • ERA: 4.42
  • WHIP: 1.31

Away Record: 37-41 • Home Record: 43-37
Last 5 Games: 3-2 (4.8 RPG)
Last 10 Games: 7-3 (5.0 RPG)


Head-to-Head History

Tied 4–4 (Last 8 games)

  • September 24, 2025: LAD 5 @ ARI 4
  • September 23, 2025: LAD 4 @ ARI 5
  • August 31, 2025: ARI 4 @ LAD 5
  • August 30, 2025: ARI 6 @ LAD 1
  • August 29, 2025: ARI 3 @ LAD 0
  • May 21, 2025: ARI 1 @ LAD 3
  • May 20, 2025: ARI 3 @ LAD 4
  • May 19, 2025: ARI 9 @ LAD 5

Over/Under Trends

Los Angeles Dodgers’ last 10 games have averaged 8.9 total runs, with 7 games that would have cleared today’s total of 8.5.

Arizona Diamondbacks’ last 10 games have averaged 8.9 combined runs, with 7 games clearing the same number of 8.5.

Moneyline Betting Prediction

Los Angeles’ superior offensive depth, highlighted by consistent run production from multiple bats, outweighs Arizona Diamondbacks’ recent home form. Their ability to generate steady scoring across the last 10 games combined with a narrow head-to-head edge positions them as the sharper moneyline side to back with confidence.

This sets up cleanly for the Los Angeles Dodgers to finish on top.

Over/Under Prediction

In their last five, the Arizona Diamondbacks have produced 4.8 RPG and the Los Angeles Dodgers 4.6. With both teams averaging 9.4 runs per game recently, we’re expecting a Over 8.5 outcome.

Bookmakers

MLB Data pulled from: FanDuel, LowVig.ag, DraftKings, MyBookie.ag, BetMGM, Bovada, Fanatics, BetUS, BetRivers.

Parlamaz may earn affiliate commissions from links in this article.

MLB Predictions FAQ

What do moneyline, run line, and total mean?

Moneyline is who wins the game. Run line is a spread, usually ±1.5 runs. The total (over/under) is combined runs by both teams.

How should I size my bets?

Use a consistent unit (about 1–2% of bankroll). Singles should be most of your volume. We like parlays—smart ones. Keep legs tight (2–3), cap risk to 0.25–0.5u, and pass when the price isn’t there.

John Tamburino

John TamburinoVerified

Lead Analyst — data-first, former college baseball.

John Tamburino grew up on travel baseball and three years of varsity basketball, then played college baseball before shifting to analytics. He still watches everything—from weekday tennis to all major league sports—and will never forget the Diamondbacks’ World Series run. At Parlamaz, John blends trusted data feeds with matchup context to find real value—no fluff, no paywalls.