Prediction Details

MLB Prediction: New York Mets vs Chicago Cubs (Wednesday, September 24 at 08:05 PM ET)

Introduction

Updated

NYM @ CHCNYM -103CHC -122O/U 7.0
Market / Trend NYM CHC
Moneyline -103 -122
Total (O/U) 7.0
Run Line +1.5 (-211) -1.5 (170)
Last 5 RPG 6.4 2.8
Record 81–76 88–69
Lines: BetMGM, BetRivers, Bovada, Caesars +4 more

More MLB picks: New York Mets · Chicago Cubs

The Cubs enter this matchup analysis on a five-game skid, but their overall 88-69 record and strong home profile still demand respect against the Mets. New York has averaged 6.4 runs per game across its last five contests, yet its 32-44 road record exposes vulnerability away from home. With both lineups showing consistent power numbers and recent totals trending high, this MLB prediction leans firmly toward the Cubs to rebound and the run count to push past the posted number.

Game Time

Starts in 18h 52m

Opening pitch at Wednesday, September 24 at 08:05 PM ET at iconic Wrigley Field, wind dictates the number.

Odds & Spread Line

  • New York Mets: -103
  • Chicago Cubs: -122

Total: 7

  • Run Line — New York Mets: +1.5 (-211)
  • Run Line — Chicago Cubs: -1.5 (+170)

Latest Team Records

New York Mets: 81-76 (Win %: 0.516)
Chicago Cubs: 88-69 (Win %: 0.561)

Injury Report

Both teams are currently healthy with no major injury concerns.

Key Player Stats

New York Mets

  • Pete Alonso: 0.274 AVG, 37 HR, 122 RBI
  • Juan Soto: 0.267 AVG, 42 HR, 104 RBI
  • Francisco Lindor: 0.267 AVG, 28 HR, 80 RBI

Chicago Cubs

  • Michael Busch: 0.256 AVG, 30 HR, 82 RBI
  • Pete Crow-Armstrong: 0.245 AVG, 29 HR, 90 RBI
  • Seiya Suzuki: 0.242 AVG, 27 HR, 91 RBI

Team Analysis

New York Mets

The Mets have managed a 3-2 record over their last five games, producing 6.4 runs per game in that span and showing flashes of offensive rhythm. Despite this recent scoring push, their 32-44 road record exposes a pattern of inconsistency whenever they leave New York. Pete Alonso and Juan Soto provide the power the lineup leans on, but the team’s ability to sustain that output away from home remains questionable against a Cubs team with a superior overall record.

Over the last 10 games, the Mets have split results at 5-5 while averaging 5.4 runs per game, a balanced but not dominant trend. Francisco Lindor has added depth to the lineup, yet their reliance on big bats has not consistently solved their road struggles. With a sub-.500 away mark, bettors must weigh whether the Mets’ recent offensive surge can truly translate in Chicago against a Cubs side built to defend home turf.

  • Batting Average: 0.25
  • Total Runs Scored: 739
  • Home Runs: 215
  • OBP: 0.327
  • SLG: 0.429
  • OPS: 0.756
  • ERA: 3.99
  • WHIP: 1.33

Away Record: 32-44 • Home Record: 49-32
Last 5 Games: 3-2 (6.4 RPG)
Last 10 Games: 5-5 (5.4 RPG)


Chicago Cubs

The Cubs’ 0-5 skid in their last five games with just 2.8 runs per contest highlights a slump, but their 46-30 home record shows why they remain dangerous at Wrigley. Michael Busch’s power numbers anchor an offense that is still built to break out of slumps quickly. Despite the recent dip, the Cubs’ strong season-long form and home dominance make them the more reliable side compared to the Mets’ road woes.

Over the last 10 games, Chicago has gone 4-6 while averaging 3.8 runs per game, but their consistency at home has been the stabilizer all year. Pete Crow-Armstrong and Seiya Suzuki provide balance to the order, ensuring multiple threats across the lineup. With a higher overall win percentage and proven home-field strength, the Cubs are positioned to capitalize against a Mets team that has struggled away from Citi Field.

  • Batting Average: 0.249
  • Total Runs Scored: 750
  • Home Runs: 209
  • OBP: 0.32
  • SLG: 0.426
  • OPS: 0.746
  • ERA: 3.82
  • WHIP: 1.18

Away Record: 42-39 • Home Record: 46-30
Last 5 Games: 0-5 (2.8 RPG)
Last 10 Games: 4-6 (3.8 RPG)


Head-to-Head History

New York Mets lead 3–1 (Last 4 games)

  • September 23, 2025: NYM 9 @ CHC 7
  • May 11, 2025: CHC 2 @ NYM 6
  • May 10, 2025: CHC 6 @ NYM 5
  • May 09, 2025: CHC 2 @ NYM 7

Over/Under Trends

New York Mets’ last 10 games have averaged 9.9 total runs, with 6 games that would have cleared today’s total of 7.

Chicago Cubs’ last 10 games have averaged 7.5 combined runs, with 5 games clearing the same number of 7.

Moneyline Betting Prediction

The Cubs’ superior overall record, strong 46-30 home mark, and lineup depth anchored by Michael Busch, Pete Crow-Armstrong, and Seiya Suzuki provide a clear edge over a Mets team that has struggled to translate offensive bursts on the road. Despite a poor recent stretch, the Cubs’ home dominance and season-long consistency make them the more reliable side to back in this spot.

Confidence sits with the Chicago Cubs based on recent profiles.

Over/Under Prediction

Last five form shows the Chicago Cubs at 2.8 RPG and the New York Mets at 6.4, giving context for the number.

These teams are combining for 9.2 runs per game recently — above the posted total of 7.0. That points toward the Over 7.0.

Bookmakers

Available at: FanDuel, MyBookie.ag, Bovada, Fanatics, Caesars, DraftKings, BetMGM, BetRivers.

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MLB Predictions FAQ

How should I size my bets?

Use a consistent unit (about 1–2% of bankroll). Singles should be most of your volume. We like parlays—smart ones. Keep legs tight (2–3), cap risk to 0.25–0.5u, and pass when the price isn’t there.

What’s a good price range for today’s pick (Sep 24, 2025)?

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How does Parlamaz make New York Mets vs Chicago Cubs MLB predictions?

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John Tamburino

John TamburinoVerified

Lead Analyst — data-first, former college baseball.

John Tamburino grew up on travel baseball and three years of varsity basketball, then played college baseball before shifting to analytics. He still watches everything—from weekday tennis to all major league sports—and will never forget the Diamondbacks’ World Series run. At Parlamaz, John blends trusted data feeds with matchup context to find real value—no fluff, no paywalls.