Prediction Details

MLB Prediction: Baltimore Orioles vs Chicago White Sox (Monday, September 15 at 07:40 PM ET)

Introduction

Updated

BAL @ CWSBAL -152CWS +123O/U 8.0
Market / Trend BAL CWS
Moneyline -152 +123
Total (O/U) 8.0
Run Line -1.5 (115) +1.5 (-135)
Last 5 RPG 2.4 2.8
Record 69–79 57–92
Lines: BetMGM, BetOnline.ag, BetRivers, BetUS +6 more

More MLB picks: Baltimore Orioles · Chicago White Sox

The Orioles enter this matchup analysis after averaging just 2.4 runs per game across their last 5 contests, while the White Sox have managed 2.8 in the same span. Despite both offenses trending cold, Baltimore Orioles’ superior season record and head-to-head dominance point to a decisive edge. With Chicago struggling to sustain run production, this MLB prediction favors the Orioles’ ability to control tempo and keep scoring suppressed, setting the stage for value on the under.

Game Time

Starts in 23h 51m

Game time: Monday, September 15 at 07:40 PM ET at Guaranteed Rate Field, power alleys invite damage.

Odds & Spread Line

  • Baltimore Orioles: -152
  • Chicago White Sox: +123

Total: 8

  • Run Line — Baltimore Orioles: -1.5 (+115)
  • Run Line — Chicago White Sox: +1.5 (-135)

Latest Team Records

Baltimore Orioles: 69-79 (Win %: 0.466)
Chicago White Sox: 57-92 (Win %: 0.383)

Injury Report

Baltimore Orioles are missing Colin Selby (Hamstring), listed as 15-Day-IL; Gary Sanchez (Knee), listed as 60-Day-IL.

Chicago White Sox are missing Max Stassi (Undisclosed), listed as Day-To-Day.

Key Player Stats

Baltimore Orioles

  • Gunnar Henderson: 0.27 AVG, 16 HR, 62 RBI
  • Jackson Holliday: 0.252 AVG, 17 HR, 55 RBI
  • Jordan Westburg: 0.276 AVG, 15 HR, 34 RBI

Chicago White Sox

  • Lenyn Sosa: 0.263 AVG, 20 HR, 68 RBI
  • Andrew Benintendi: 0.243 AVG, 19 HR, 60 RBI
  • Mike Tauchman: 0.267 AVG, 8 HR, 39 RBI

Team Analysis

Baltimore Orioles

The Orioles sit at 69-79, a mark that spotlights inconsistency but still a stronger profile than their opponent. Their last 5 Games: 2-3 (2.4 RPG) reflect an offense that has struggled to string together rallies, yet their last 10 Games: 6-4 (3.0 RPG) shows a broader trend of stabilizing form. Gunnar Henderson’s power and Jackson Holliday’s run production offer the kind of upside that gives Baltimore the edge when games tighten, especially on the road where they’ve already banked 33 wins.

Jordan Westburg’s balanced hitting approach adds depth to a lineup that needs timely contact more than sheer volume. With their away record at 33-42, the Orioles have proven competitive enough outside of Baltimore to challenge weaker opposition, and Chicago’s numbers make this a favorable spot. Their ability to keep games low-scoring aligns with their recent run production, making them the more disciplined side in this matchup.

  • Batting Average: 0.239
  • Total Runs Scored: 633
  • Home Runs: 174
  • OBP: 0.307
  • SLG: 0.399
  • OPS: 0.705
  • ERA: 4.58
  • WHIP: 1.37

Away Record: 33-42 • Home Record: 36-38
Last 5 Games: 2-3 (2.4 RPG)
Last 10 Games: 6-4 (3.0 RPG)


Chicago White Sox

The White Sox’s 57-92 record shows a team that has failed to find rhythm all season. Their Last 5 Games: 2-3 (2.8 RPG) highlight an offense that remains inconsistent, with Lenyn Sosa’s power numbers overshadowed by the lack of sustained support. Even at home, where they hold a 32-43 record, the production has not been reliable enough to back them against a more structured Baltimore side.

Andrew Benintendi provides some stability, but Mike Tauchman’s contributions have not been enough to lift a lineup that struggles in key moments. Their Last 10 Games: 5-5 (4.2 RPG) suggest a team capable of modest output, yet defensive reliability has not translated into wins. Given Baltimore Orioles’ recent head-to-head dominance, Chicago’s home-field advantage looks muted in this matchup.

  • Batting Average: 0.235
  • Total Runs Scored: 598
  • Home Runs: 150
  • OBP: 0.304
  • SLG: 0.376
  • OPS: 0.679
  • ERA: 4.22
  • WHIP: 1.36

Away Record: 25-50 • Home Record: 32-43
Last 5 Games: 2-3 (2.8 RPG)
Last 10 Games: 5-5 (4.2 RPG)


Head-to-Head History

Baltimore Orioles lead 3–0 (Last 3 games)

  • June 01, 2025: CHW 2 @ BAL 3
  • May 31, 2025: CHW 2 @ BAL 4
  • May 30, 2025: CHW 1 @ BAL 2

Over/Under Trends

Baltimore Orioles’ last 10 games have averaged 7.1 total runs, with 3 games that would have cleared today’s total of 8.

Chicago White Sox’s last 10 games have averaged 8.6 combined runs, with 5 games clearing the same number of 8.

Moneyline Betting Prediction

Baltimore Orioles’ steadier 6-4 mark across their last 10 games, combined with their 3-0 head-to-head sweep earlier this season, establishes them as the reliable side. With Henderson, Holliday, and Westburg delivering enough offensive balance to back a superior record, the Orioles project to control tempo and extend their dominance over a struggling Chicago roster.

Form and matchup edges favor the Baltimore Orioles — back them.

Over/Under Prediction

Recent five-game scoring: the Chicago White Sox are at 2.8 RPG and the Baltimore Orioles at 2.4 — a useful baseline against the total.

These teams are combining for 5.2 runs per game recently — below the posted total of 8.0. That points toward the Under 8.0.

Bookmakers

Data pulled from: FanDuel, LowVig.ag, BetOnline.ag, Caesars, MyBookie.ag, DraftKings, BetUS, BetMGM, Bovada, BetRivers.

Parlamaz may earn affiliate commissions from links in this article.

MLB Predictions FAQ

What do moneyline, run line, and total mean?

Moneyline is who wins the game. Run line is a spread, usually ±1.5 runs. The total (over/under) is combined runs by both teams.

How often are picks updated?

Daily. We update for confirmed lineups, injuries, and market moves. Check back near first pitch for final notes.

John Tamburino

John TamburinoVerified

Lead Analyst — data-first, former college baseball.

John Tamburino grew up on travel baseball and three years of varsity basketball, then played college baseball before shifting to analytics. He still watches everything—from weekday tennis to all major league sports—and will never forget the Diamondbacks’ World Series run. At Parlamaz, John blends trusted data feeds with matchup context to find real value—no fluff, no paywalls.