- September 12, 2025
- Views 173
MLB Prediction: St. Louis Cardinals vs Milwaukee Brewers (Saturday, September 13 at 08:15 PM ET)
Introduction
| Market / Trend | STL | MIL |
|---|---|---|
| Moneyline | +143 | -179 |
| Total (O/U) | 7.5 | |
| Run Line | +1.5 (-156) | -1.5 (131) |
| Last 5 RPG | 2.6 | 5.0 |
| Record | 72–76 | 90–58 |
| Lines: BetMGM, BetOnline.ag, BetRivers, BetUS +6 more | ||
More MLB picks: St. Louis Cardinals · Milwaukee Brewers
Milwaukee enters this matchup analysis with a commanding 90-58 record while St. Louis has stumbled to 72-76, including just 1-4 in its last five with a weak 2.6 runs per game average. That slump is particularly damaging against a Brewers team that has been steady at home with a 47-26 mark and consistent offensive balance. With the Cardinals’ road struggles colliding with Milwaukee Brewers’ superior form and depth, this MLB prediction points firmly toward a Brewers win in a lower-scoring contest.
Game Time
First pitch is set for Saturday, September 13 at 08:15 PM ET inside American Family Field, indoor air keeps offense lively.
Odds & Spread Line
- St. Louis Cardinals: +143
- Milwaukee Brewers: -179
Total: 7.5
- Run Line — St. Louis Cardinals: +1.5 (-156)
- Run Line — Milwaukee Brewers: -1.5 (+131)
Latest Team Records
St. Louis Cardinals: 72-76 (Win %: 0.486)
Milwaukee Brewers: 90-58 (Win %: 0.608)
Injury Report
The St. Louis Cardinals are currently healthy with no major injury concerns.
Milwaukee Brewers are missing Garrett Mitchell (Shoulder), listed as 60-Day-IL.
Key Player Stats
St. Louis Cardinals
- Willson Contreras: 0.253 AVG, 20 HR, 78 RBI
- Alec Burleson: 0.282 AVG, 17 HR, 62 RBI
- Ivan Herrera: 0.279 AVG, 15 HR, 56 RBI
Milwaukee Brewers
- Christian Yelich: 0.267 AVG, 27 HR, 93 RBI
- Brice Turang: 0.289 AVG, 18 HR, 74 RBI
- Jackson Chourio: 0.278 AVG, 20 HR, 72 RBI
Team Analysis
St. Louis Cardinals
The Cardinals’ 72-76 record reflects a team that has failed to generate momentum, especially on the road where they sit at 31-42. Their last 5 games show a 1-4 mark with just 2.6 runs per game, highlighting an offense that has fallen into a slump. Even with Willson Contreras providing occasional production, the overall lineup has lacked consistency and confidence in high-leverage spots.
Over the last 10 games, St. Louis is just 4-6 while averaging 2.8 runs, which emphasizes how limited their scoring has been. Alec Burleson and Ivan Herrera have shown flashes, but those efforts have not been enough to compensate for the broader lack of rhythm. Given their weak road form and current offensive drought, the Cardinals project as an unreliable betting side in this matchup.
- Batting Average: 0.244
- Total Runs Scored: 629
- Home Runs: 138
- OBP: 0.313
- SLG: 0.379
- OPS: 0.692
- ERA: 4.26
- WHIP: 1.31
Away Record: 31-42 • Home Record: 41-34
Last 5 Games: 1-4 (2.6 RPG)
Last 10 Games: 4-6 (2.8 RPG)
Milwaukee Brewers
The Brewers have built a 90-58 record behind consistent execution and a 47-26 home mark that reinforces their edge at this venue. Their last 5 games show a 2-3 split, but a steady 5.0 runs per game output signals that the offense remains reliable. Christian Yelich continues to anchor the lineup with power and run production, ensuring Milwaukee maintains scoring pressure.
Over their last 10 contests, Milwaukee sits at 5-5 while averaging 4.8 runs, which is still well above what the Cardinals have produced recently. Brice Turang’s steady contact and Jackson Chourio’s balanced contributions give the Brewers multiple avenues to manufacture runs. With a strong pitching staff backing this offense, Milwaukee Brewers’ stability at home makes them the clear betting side.
- Batting Average: 0.26
- Total Runs Scored: 743
- Home Runs: 157
- OBP: 0.333
- SLG: 0.408
- OPS: 0.741
- ERA: 3.63
- WHIP: 1.23
Away Record: 43-32 • Home Record: 47-26
Last 5 Games: 2-3 (5.0 RPG)
Last 10 Games: 5-5 (4.8 RPG)
Head-to-Head History
Milwaukee Brewers lead 5–3 (Last 8 games)
- September 12, 2025: STL 2 @ MIL 8
- June 15, 2025: STL 2 @ MIL 3
- June 14, 2025: STL 8 @ MIL 5
- June 13, 2025: STL 2 @ MIL 3
- June 12, 2025: STL 0 @ MIL 6
- April 27, 2025: MIL 7 @ STL 1
- April 26, 2025: MIL 5 @ STL 6
- April 25, 2025: MIL 2 @ STL 3
Over/Under Trends
St. Louis Cardinals’ last 10 games have averaged 7.5 total runs, with 4 games that would have cleared today’s total of 7.5.
Milwaukee Brewers’ last 10 games have averaged 8.6 combined runs, with 6 games clearing the same number of 7.5.
Moneyline Betting Prediction
Milwaukee Brewers’ superior 47-26 home record, consistent scoring near five runs per game, and clear 5-3 head-to-head edge firmly position them as the stronger side. With Christian Yelich driving production and balanced contributions from Brice Turang and Jackson Chourio, the Brewers project to control tempo against a Cardinals team stuck in a slump.
Form and matchup edges favor the Milwaukee Brewers — back them.
Over/Under Prediction
Last five form shows the Milwaukee Brewers at 5.0 RPG and the St. Louis Cardinals at 2.6, giving context for the number.
These teams are combining for 7.6 runs per game recently — right around the posted total of 7.5. That points toward the Over 7.5.
Bookmakers
Lines retrieved from: BetOnline.ag, LowVig.ag, Caesars, FanDuel, MyBookie.ag, DraftKings, Fanatics, BetMGM.
Parlamaz may earn affiliate commissions from links in this article.
MLB Predictions FAQ
How does Parlamaz make St. Louis Cardinals vs Milwaukee Brewers MLB predictions?
We use trusted data feeds and real-time odds to model each matchup. We weight the numbers that move lines—team form, matchup history, injuries, park factors, totals trends, and betting momentum—then compare our price to the market to find value. All signal, no noise. No paywalls.
How should I size my bets?
Use a consistent unit (about 1–2% of bankroll). Singles should be most of your volume. We like parlays—smart ones. Keep legs tight (2–3), cap risk to 0.25–0.5u, and pass when the price isn’t there.
John TamburinoVerified
Lead Analyst — data-first, former college baseball.
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