- August 25, 2025
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MLB Prediction: Chicago Cubs vs San Francisco Giants (Tuesday, August 26 at 09:45 PM ET)
Introduction
Market / Trend | CHC | SF |
---|---|---|
Moneyline | -141 | +115 |
Total (O/U) | 7.5 | |
Run Line | -1.5 (130) | +1.5 (-153) |
Last 5 RPG | 4.8 | 4.0 |
Record | 76–55 | 63–68 |
Lines: BetMGM, BetOnline.ag, BetUS, Bovada +6 more |
More MLB picks: Chicago Cubs · San Francisco Giants
Chicago enters this matchup analysis riding an 8-2 surge across its last 10, powered by 4.1 runs per game and a consistent road presence. San Francisco, meanwhile, has dropped 6 of its last 10 with uneven offensive output, scoring just 3.9 runs per game in that stretch. With the Cubs showing sharper form and stronger lineup productivity, this MLB prediction leans firmly toward Chicago Cubs’ momentum and a higher-scoring contest than the market suggests.
Game Time
This one goes at Tuesday, August 26 at 09:45 PM ET inside Oracle Park, fly balls die quickly.
Odds & Spread Line
- Chicago Cubs: -141
- San Francisco Giants: +115
Total: 7.5
- Run Line — Chicago Cubs: -1.5 (+130)
- Run Line — San Francisco Giants: +1.5 (-153)
Latest Team Records
Chicago Cubs: 76-55 (Win %: 0.58)
San Francisco Giants: 63-68 (Win %: 0.481)
Injury Report
Chicago Cubs are missing Miguel Amaya (Ankle), listed as 10-Day-IL; Michael Soroka (Shoulder), listed as 15-Day-IL; Nick Madrigal (Shoulder), listed as 60-Day-IL. No other significant injuries are reported.
San Francisco Giants are missing Randy Rodriguez (Arm), listed as Day-To-Day; Landen Roupp (Knee), listed as 15-Day-IL; Erik Miller (Elbow), listed as 60-Day-IL; Jerar Encarnacion (Hamstring), listed as 10-Day-IL. No other significant injuries are reported.
Key Player Stats
Chicago Cubs
- Pete Crow-Armstrong: 0.254 AVG, 28 HR, 82 RBI
- Seiya Suzuki: 0.243 AVG, 27 HR, 87 RBI
- Michael Busch: 0.262 AVG, 24 HR, 74 RBI
San Francisco Giants
- Rafael Devers: 0.252 AVG, 25 HR, 83 RBI
- Willy Adames: 0.225 AVG, 22 HR, 65 RBI
- Heliot Ramos: 0.26 AVG, 15 HR, 55 RBI
Team Analysis
Chicago Cubs
The Cubs enter this contest with a 4-1 mark in their last 5 games, averaging 4.8 runs per outing, which emphasizes their offensive rhythm. Pete Crow-Armstrong has been central to this surge, anchoring a lineup that consistently pressures opposing pitching. Their 35-30 road record adds confidence that production translates away from home, a key edge in this spot.
Seiya Suzuki and Michael Busch give Chicago depth across the order, ensuring scoring threats beyond just the middle of the lineup. The Cubs’ 8-2 record in their last 10 games reflects sustained form rather than a short burst, with pitching stability backing the bats. Taken together, this profile makes them a reliable side to back against a struggling opponent.
- Batting Average: 0.249
- Total Runs Scored: 648
- Home Runs: 178
- OBP: 0.319
- SLG: 0.428
- OPS: 0.747
- ERA: 3.76
- WHIP: 1.19
Away Record: 35-30 • Home Record: 41-25
Last 5 Games: 4-1 (4.8 RPG)
Last 10 Games: 8-2 (4.1 RPG)
San Francisco Giants
The Giants have stumbled to a 2-3 clip over their last 5, with 4.0 runs per game failing to cover for defensive lapses. Rafael Devers remains their most reliable offensive threat, but his contributions have not been enough to mask overall inconsistency. With just a 30-33 home record, San Francisco has not leveraged its ballpark effectively this season.
Willy Adames and Heliot Ramos provide some power options, yet the team’s 4-6 stretch across the last 10 highlights a lack of sustained scoring. Even when the lineup flashes, run support has been unreliable relative to league averages. Against a surging Cubs team, this inconsistency makes the Giants a vulnerable side in this matchup.
- Batting Average: 0.231
- Total Runs Scored: 530
- Home Runs: 128
- OBP: 0.308
- SLG: 0.376
- OPS: 0.684
- ERA: 3.74
- WHIP: 1.29
Away Record: 33-35 • Home Record: 30-33
Last 5 Games: 2-3 (4.0 RPG)
Last 10 Games: 4-6 (3.9 RPG)
Head-to-Head History
San Francisco Giants lead 2–1 (Last 3 games)
- May 07, 2025: SF 3 @ CHC 1
- May 06, 2025: SF 14 @ CHC 5
- May 05, 2025: SF 2 @ CHC 9
Over/Under Trends
Chicago Cubs’ last 10 games have averaged 7.0 total runs, with 2 games that would have cleared today’s total of 7.5.
San Francisco Giants’ last 10 games have averaged 8.2 combined runs, with 6 games clearing the same number of 7.5.
Moneyline Betting Prediction
Chicago Cubs’ 8-2 run over the last 10, combined with steady road performance and multiple productive bats, gives them a clear edge in this matchup. With San Francisco inconsistent at home and unable to string together offense despite Devers’ efforts, the Cubs’ balanced attack makes them the decisive side to back here.
The Chicago Cubs are the sharp side on form and splits.
Over/Under Prediction
Last five form shows the San Francisco Giants at 4.0 RPG and the Chicago Cubs at 4.8, giving context for the number.
These teams are combining for 8.8 runs per game recently — above the posted total of 7.5. That points toward the Over 7.5.
Bookmakers
Data pulled from: FanDuel, MyBookie.ag, BetOnline.ag, LowVig.ag, Caesars, DraftKings, Bovada, BetMGM, BetUS, Fanatics.
Parlamaz may earn affiliate commissions from links in this article.
MLB Predictions FAQ
How often are picks updated?
Daily. We update for confirmed lineups, injuries, and market moves. Check back near first pitch for final notes.
What’s a good price range for today’s pick (Aug 26, 2025)?
We list a target price in the post. If the market moves past that number, reduce stake size or pass instead of chasing worse odds.
How should I size my bets?
Use a consistent unit (about 1–2% of bankroll). Singles should be most of your volume. We like parlays—smart ones. Keep legs tight (2–3), cap risk to 0.25–0.5u, and pass when the price isn’t there.

John TamburinoVerified
Lead Analyst — data-first, former college baseball.
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