Prediction Details

MLB Prediction: Cleveland Guardians vs Arizona Diamondbacks (Monday, August 18 at 09:40 PM ET)

Introduction

Updated


CLE @ ARI

CLE -102
ARI -116
O/U 9.0
Market / Trend CLE ARI
Moneyline -102 -116
Total (O/U) 9.0
Run Line -1.5 (+162) +1.5 (-196)
Last 5 RPG 3.6 5.8
Record 63–59 60–64
Updated Aug 17, 2025 11:40 PM ET
Lines: FanDuel

More MLB picks: Cleveland Guardians · Arizona Diamondbacks

Arizona enters this interleague matchup analysis against Cleveland with steadier scoring rhythm, while the Guardians have slumped to a 1-4 mark across their last five. That split highlights a clear contrast in form, setting up a strong MLB prediction angle. Cleveland Guardians’ road record is slightly above .500, but Arizona Diamondbacks’ balanced home profile and deeper lineup efficiency make them the sharper side. With both teams’ recent run production averaging below elite levels, the betting edge aligns with the Diamondbacks and a lean toward the Under.

Game Time

Starts in 22h 2m

Scheduled for Monday, August 18 at 09:40 PM ET under the roof at Chase Field, a balanced scoring environment.

Odds & Spread Line

  • Cleveland Guardians: -102
  • Arizona Diamondbacks: -116

Total: 9

  • Run Line — Cleveland Guardians: -1.5 (+162)
  • Run Line — Arizona Diamondbacks: +1.5 (-196)

Latest Team Records

Cleveland Guardians: 63-59 (Win %: 0.516)
Arizona Diamondbacks: 60-64 (Win %: 0.484)

Injury Report

The Cleveland Guardians are currently healthy with no major injury concerns.

Arizona Diamondbacks are missing Ryan Thompson (Shoulder), listed as 15-Day-IL; Gabriel Moreno (Finger), listed as 60-Day-IL; Ildemaro Vargas (Foot), listed as 10-Day-IL. No other significant injuries are reported.

Key Player Stats

Cleveland Guardians

  • Jose Ramirez: 0.293 AVG, 25 HR, 64 RBI
  • Kyle Manzardo: 0.24 AVG, 21 HR, 54 RBI
  • Steven Kwan: 0.279 AVG, 10 HR, 40 RBI

Arizona Diamondbacks

  • Ketel Marte: 0.298 AVG, 23 HR, 56 RBI
  • Geraldo Perdomo: 0.285 AVG, 13 HR, 79 RBI
  • Corbin Carroll: 0.248 AVG, 26 HR, 63 RBI

Team Analysis

Cleveland Guardians

The Guardians’ 1-4 record across their last five games lays bare a team searching for consistency at the plate. Despite Jose Ramirez’s steady production, overall scoring has lagged with just 3.6 runs per game in that stretch. Their 32-29 road record shows they can compete away from home, but the lack of recent momentum makes them a risky side against a more potent lineup.

Kyle Manzardo and Steven Kwan add complementary pieces, yet the Guardians’ offense has been unable to sustain pressure. With a neutral 5-5 mark over the last ten, Cleveland has alternated between competitive outings and underwhelming efforts. Against a Diamondbacks squad with more consistent home scoring, their current rhythm does not inspire confidence for bettors seeking stability.

  • Batting Average: 0.227
  • Total Runs Scored: 484
  • Home Runs: 129
  • OBP: 0.299
  • SLG: 0.375
  • OPS: 0.674
  • ERA: 3.89
  • WHIP: 1.31

Away Record: 32-29 • Home Record: 31-31
Last 5 Games: 1-4 (3.6 RPG)
Last 10 Games: 5-5 (4.2 RPG)


Arizona Diamondbacks

Arizona Diamondbacks’ recent 2-3 stretch in the last five games has still featured 5.8 runs per outing, showing their ability to generate offense even in losses. Ketel Marte’s consistency has anchored the lineup, while Geraldo Perdomo’s run production has elevated their scoring ceiling. At home, a 30-30 record reflects balance, and when combined with their superior offensive metrics, it positions them well in this matchup.

Over the last ten games, the Diamondbacks are 6-4 with an impressive 6.3 runs per contest, signaling sharper rhythm and confidence at the plate. Corbin Carroll’s power presence adds another layer that Cleveland Guardians’ recent form struggles to match. With steadier scoring and the advantage of playing at home, Arizona holds the stronger betting profile in this interleague meeting.

  • Batting Average: 0.25
  • Total Runs Scored: 613
  • Home Runs: 174
  • OBP: 0.325
  • SLG: 0.44
  • OPS: 0.765
  • ERA: 4.57
  • WHIP: 1.34

Away Record: 30-35 • Home Record: 30-30
Last 5 Games: 2-3 (5.8 RPG)
Last 10 Games: 6-4 (6.3 RPG)


Head-to-Head History

No recent matchups between these teams in 2025.

Over/Under Trends

Cleveland Guardians’ last 10 games have averaged 9.2 total runs, with 5 games that would have cleared today’s total of 9.

Arizona Diamondbacks’ last 10 games have averaged 11.0 combined runs, with 7 games clearing the same number of 9.

Moneyline Betting Prediction

The Diamondbacks’ stronger recent scoring profile, balanced home record, and lineup depth led by Ketel Marte and Corbin Carroll give them the decisive edge over a slumping Guardians team. Cleveland Guardians’ 1-4 mark in their last five reflects inconsistency, while Arizona Diamondbacks’ ability to sustain over 6 runs per game in their last ten signals a sharper trajectory. With those contrasts in rhythm and output, the Diamondbacks are the clear side to back.

This sets up cleanly for the Arizona Diamondbacks to finish on top.

Over/Under Prediction

In their last five, the Arizona Diamondbacks have produced 5.8 RPG and the Cleveland Guardians 3.6. That output frames how this total sets up.

These teams are combining for 9.4 runs per game recently — above the posted total of 9.0. That points toward a Over 9.0.

Bookmakers

Data pulled from: FanDuel.

Parlamaz may earn affiliate commissions from links in this article.

MLB Predictions FAQ

How does Parlamaz make Cleveland Guardians vs Arizona Diamondbacks MLB predictions?

We use trusted data feeds and real-time odds to model each matchup. We weight the numbers that move lines—team form, matchup history, injuries, park factors, totals trends, and betting momentum—then compare our price to the market to find value. All signal, no noise. No paywalls.

What do moneyline, run line, and total mean?

Moneyline is who wins the game. Run line is a spread, usually ±1.5 runs. The total (over/under) is combined runs by both teams.

What’s a good price range for today’s pick (Aug 18, 2025)?

We list a target price in the post. If the market moves past that number, reduce stake size or pass instead of chasing worse odds.

How should I size my bets?

Use a consistent unit (about 1–2% of bankroll). Singles should be most of your volume. We like parlays — smart ones. Build them from real edges, keep legs tight (2–3), cap risk to 0.25–0.5u, and pass when the price isn’t there.

How often are picks updated?

Daily. We update for confirmed lineups, injuries, and market moves. Check back near first pitch for final notes.

John Tamburino

John TamburinoVerified

Lead Analyst — data-first, former college baseball.

John Tamburino grew up on travel baseball and three years of varsity basketball, then played college baseball before shifting to analytics. He still watches everything—from weekday tennis to UFC—and will never forget the Diamondbacks’ 2001 run. At Parlamaz, John blends trusted data feeds with matchup context to find real value—no fluff, no paywalls.