Introduction

In a gripping American and National League showdown, the Washington Nationals are set to challenge the Houston Astros. With their distinct forms, this MLB prediction takes you right into the heart of the action, tallying both the Nationals’ stride on the road, and the Astros’ home-ground fortitude.

Game Time

The first pitch is scheduled for Monday, July 28 at 08:10 PM ET in Minute Maid Park, where right-handed power can thrive.

Moneyline Odds

Washington Nationals: +190
Houston Astros: -233
Over/Under Line: 7.5

Latest Team Records

Washington Nationals: 42-62 (Win %: 0.404)
Houston Astros: 60-45 (Win %: 0.571)

Injury Report

The Washington Nationals are currently healthy with no major injury concerns.

Key injuries for the Houston Astros include:

• Jake Meyers (Calf) – Status: 10-Day-IL.
• Shawn Dubin (Forearm) – Status: 15-Day-IL.

Key Player Stats

Washington Nationals

• James Wood: 0.266 AVG, 24 HR, 70 RBI
• CJ Abrams: 0.271 AVG, 13 HR, 40 RBI
• Nathaniel Lowe: 0.225 AVG, 15 HR, 62 RBI

Houston Astros

• Jeremy Pena: 0.322 AVG, 11 HR, 40 RBI
• Jose Altuve: 0.281 AVG, 17 HR, 53 RBI
• Isaac Paredes: 0.259 AVG, 19 HR, 50 RBI

Team Analysis

Washington Nationals

The Washington Nationals are in dire need to better their rhythm, after several hard losses on the road. Their recent form, however, offers some optimism. The team recorded three wins in their last five games — mostly due to the offensive prowess of players such as James Wood and CJ Abrams.

While road victories have been few and far between, Washington have shown they can shine away from home. It’s crucial they maintain this momentum to ward off the Astros’ charge. Their away record is less than stellar, but if their top performers come to play, this game might turn out closer than expected.

• Batting Average: 0.244
• Total Runs Scored: 449
• Home Runs: 101
• OPS: 0.698
• ERA: 5.14
• WHIP: 1.41

Away Record: 22-31 • Home Record: 21-31
Last 5 Games: 3-2 (4.4 RPG)
Last 10 Games: 5-5 (4.0 RPG)

Houston Astros

The Houston Astros have been unswerving on home soil, but their recent scoring trend has been uninspiring. With one victory in their last five games, the Astros need a jolt. Players like Jeremy Pena and Isaac Paredes have had commendable performances, but as of late, their bat power hasn’t been enough to steer the team to regular victories.

The Astros’ home record should give them some furrow of confidence, as they have been notably resilient at home. A significant boost in their offensive production could change the course of this matchup, and the Astros will be looking to leverage their home advantage to turn the tide.

• Batting Average: 0.257
• Total Runs Scored: 455
• Home Runs: 116
• OPS: 0.728
• ERA: 3.7
• WHIP: 1.19

Away Record: 27-23 • Home Record: 33-23
Last 5 Games: 1-4 (2.2 RPG)
Last 10 Games: 4-6 (3.8 RPG)

Head-to-Head History

No recent matchups between these teams in 2025.

Over/Under Trends

Washington Nationals’ last 10 games have averaged 8.5 total runs per game, with 6 of those going over the posted total of 7.5.

Houston Astros’ last 10 games have seen an average of 9.3 combined runs, with 5 games clearing the same line of 7.5.

Moneyline Betting Prediction

A combination of the Astros’ home form, recent player performances, and the Nationals’ tepid road record highlights a clear choice. Hold onto your seats because this game is bound to be electrifying. But when the dust settles, expect the Houston Astros to emerge victorious.

The Houston Astros are well-positioned to handle business.

Over/Under Prediction

Averaging 2.2 runs per game lately, the Houston Astros are ramping up offensively, while the Washington Nationals are putting up 4.4. This spells an enticing battle between offensives in the upcoming matchup.

These teams are combining for 6.6 runs per game recently — below the posted total of 7.5, a crucial pivot point in betting markets. Our pick is Under 7.5.

Bookmakers

You’ll find these markets at: FanDuel, MyBookie.ag, BetOnline.ag, LowVig.ag, Caesars, DraftKings, BetUS, Bovada, BetMGM, BetRivers, Fanatics.

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