Introduction

Get ready for an intriguing National League battle as the San Diego Padres take on the St. Louis Cardinals. With strong key players on both sides and a notable win percentage discrepancy, this showdown promises to be a rollercoaster.

Game Time

First pitch will be thrown at Saturday, July 26 at 07:15 PM ET at pitcher-friendly Busch Stadium in St. Louis.

Moneyline Odds

San Diego Padres: +136
St. Louis Cardinals: -161
Over/Under Line: 9.0

Latest Team Records

San Diego Padres have a record of 55-48 with a win percentage of 0.534, while the St. Louis Cardinals hold a record of 53-51 with a win percentage of 0.51.

Injury Report

Both teams are currently healthy with no major injury concerns.

Key Player Stats

San Diego Padres

• Manny Machado: 0.289 AVG, 19 HR, 63 RBI
• Fernando Tatis Jr.: 0.266 AVG, 17 HR, 43 RBI
• Gavin Sheets: 0.253 AVG, 14 HR, 52 RBI

St. Louis Cardinals

• Ivan Herrera: 0.315 AVG, 9 HR, 39 RBI
• Willson Contreras: 0.262 AVG, 14 HR, 61 RBI
• Alec Burleson: 0.289 AVG, 12 HR, 44 RBI

Team Analysis

San Diego Padres

The Padres have been grappling with struggles on the road, trailing behind their more successful home performance. Looking to change this narrative, there are a few Padres standouts worth noting. Both Manny Machado and Fernando Tatis Jr., with their respectable home run counts and RBIs, will be critical in shaking up the dynamics of the game. Their athletic prowess and raw talent could give San Diego the spark they need for a win.

With the Padres’ record showing that they’ve won just one out of their last five games, a turnaround is urgently needed. The Padres are looking to tap into their potential and snap out of their rut for a strong run on the road. A lot will hinge on how well they can adjust to the away conditions and capitalize on their opportunities for scoring.

• Batting Average: 0.246
• Total Runs Scored: 414
• Home Runs: 88
• OPS: 0.69
• ERA: 3.63
• WHIP: 1.24

Away Record: 24-31 • Home Record: 31-18
Last 5 Games: 1-4 (2.8 RPG)
Last 10 Games: 4-6 (3.7 RPG)

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St. Louis Cardinals

The St. Louis Cardinals enter this matchup on the back of a solid home record, the support of the home crowd fueling their performance. They’ll look to key players like Ivan Herrera and Alec Burleson to make significant contributions with their commendable batting averages. Willson Contreras will also need to bring his A-game with his impressive RBI count, which could fuel the Cardinals’ offensive prowess.

With a slightly better overall win rate than the Padres and a recent record of three wins in their last five games, the Cardinals are trending up. Their home advantage could prove vital in this matchup as they look to register another win. Undoubtedly, how well they can exploit this will set the tone for the outcome of the game.

• Batting Average: 0.253
• Total Runs Scored: 470
• Home Runs: 103
• OPS: 0.718
• ERA: 4.23
• WHIP: 1.29

Away Record: 23-31 • Home Record: 31-20
Last 5 Games: 3-2 (4.4 RPG)
Last 10 Games: 4-6 (4.0 RPG)

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Head-to-Head History

St. Louis Cardinals lead 2–0 (Last 2 games)

• 2025-07-25: SD 0 @ STL 3
• 2025-07-24: SD 7 @ STL 9

Over/Under Trends

San Diego Padres’ last 10 games have averaged 7.0 total runs per game, with 1 of those going over the posted total of 9.0.

St. Louis Cardinals’ last 10 games have seen an average of 9.6 combined runs, with 5 games clearing the same line of 9.0.

Moneyline Betting Prediction

With a strong home advantage backed by their consistent membership, the St. Louis Cardinals are in a prime position. They wield players with notable batting averages and exhibit a solid scoring consistency at home. Their recent turnaround in form, along with their impressive head-to-head history against the Padres, signifies a keen edge for the Cardinals in this matchup.

Back the St. Louis Cardinals to deliver with confidence.

Over/Under Prediction

With the Cardinals posting an average of 4.4 runs per game recently, and the Padres straggling at 2.8, the scoring imbalance could influence the total. The teams combined averages out to 7.2 total runs per game lately, falling below the Over/Under line of 9.0.

Our smart money is on the Under 9.0.

Bookmakers

These lines come from: BetOnline.ag, LowVig.ag, FanDuel, Caesars, DraftKings, MyBookie.ag, BetMGM, BetUS, Fanatics, BetRivers, Bovada.

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