- July 21, 2025
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MLB Prediction: St. Louis Cardinals vs Colorado Rockies (Monday, July 21 at 08:40 PM ET)
Introduction
Get ready for an exciting National League showdown as the St. Louis Cardinals prepare to face off against the Colorado Rockies. With the Cardinals looking to maintain their position above .500, and the Rockies hoping to put a dent in their losing record, this game is set to be a battle of wills on the diamond.
Game Time
Matchup set for Monday, July 21 at 08:40 PM ET in the hitter-friendly confines of Coors Field.
Moneyline Odds
St. Louis Cardinals: -149
Colorado Rockies: +125
Over/Under Line: 12.0
Latest Team Records
St. Louis Cardinals have a record of 51-48 with a win percentage of 0.515, while the Colorado Rockies hold a record of 24-74 with a win percentage of 0.245.
Injury Report
Both teams are currently healthy with no major injury concerns.
Key Player Stats
St. Louis Cardinals
- Alec Burleson: 0.293 AVG, 12 HR, 44 RBI
- Brendan Donovan: 0.294 AVG, 8 HR, 36 RBI
- Willson Contreras: 0.251 AVG, 12 HR, 55 RBI
Colorado Rockies
- Hunter Goodman: 0.282 AVG, 18 HR, 55 RBI
- Jordan Beck: 0.269 AVG, 11 HR, 33 RBI
- Ryan McMahon: 0.214 AVG, 15 HR, 32 RBI
Team Analysis
St. Louis Cardinals
The St. Louis Cardinals are aiming to reset after a difficult stretch. Alec Burleson and Brendan Donovan continue to be offensive bright spots, and catcher Willson Contreras brings veteran steadiness and pop. The talent is clearly there—the question is whether they can put it all together on the road.
While their road record poses challenges, the Cardinals have the tools to win if they can jump out early and sustain pressure. Execution with runners on base will be a key metric in this one.
- Batting Average: 0.252
- Total Runs Scored: 448
- Home Runs: 99
- OPS: 0.714
- ERA: 4.18
- WHIP: 1.28
Away Record: 22-29 • Home Record: 29-20
Colorado Rockies
The Colorado Rockies are showing small signs of upward movement. Hunter Goodman and Jordan Beck remain reliable pieces in the offense, with the ability to get the team rolling in the right direction. However, their biggest hurdle remains consistency, particularly at home.
For the Rockies to make an impact in this contest, they’ll need to lean on their hitters and minimize mistakes on the mound. This could be an opportunity to shift momentum and start building a better home narrative.
- Batting Average: 0.233
- Total Runs Scored: 352
- Home Runs: 95
- OPS: 0.678
- ERA: 5.55
- WHIP: 1.57
Away Record: 12-38 • Home Record: 12-37
Head-to-Head History
No recent matchups between these teams in 2025.
Moneyline Betting Prediction
Despite recent bumps, the St. Louis Cardinals have shown resilience and a more robust run-scoring capability than their opponents. With essential offensive contributors and experience on their side, they should have the edge in this matchup. The winning combination will most likely be the Cardinals feeding off their key hitters’ energy and overcoming their road challenges to secure a win.
Everything lines up for a solid outing by the St. Louis Cardinals at -149.
Bookmakers
Lines retrieved from: BetOnline.ag, Caesars, LowVig.ag, BetUS, FanDuel, Bovada, DraftKings, MyBookie.ag, BetMGM, BetRivers, Fanatics.
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