- July 21, 2025
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MLB Prediction: San Diego Padres vs Miami Marlins (Monday, July 21 at 06:40 PM ET)
Introduction
This American League and National League showdown is set to heat up as the San Diego Padres take on the Miami Marlins. These two squads are set to clash in a game that promises to be a blend of tactics and firepower. As the Padres aim to maintain their momentum and the Marlins look to turn the tide, it’s anybody’s game.
Game Time
Catch this baseball slugfest on Monday, July 21 at 06:40 PM ET. Both teams will be looking to make their mark on loanDepot Park, a venue known for its affinity with pitchers.
Moneyline Odds
San Diego Padres: +110
Miami Marlins: -130
Over/Under Line: 8.0
Latest Team Records
The San Diego Padres are charging with a solid record of 53 wins and 45 losses, currently sporting a winning percentage of 0.541. Meanwhile, the Miami Marlins sit with a record of 46 wins and 51 losses, translating into a winning percentage of 0.474.
Injury Report
Heading into this matchup, both teams are fit and firing, making this a full-strength battle that fans can’t afford to miss.
Key Player Stats
San Diego Padres
- Manny Machado: 0.287 AVG, 18 HR, 60 RBI
- Fernando Tatis Jr.: 0.266 AVG, 16 HR, 42 RBI
- Gavin Sheets: 0.259 AVG, 14 HR, 50 RBI
Miami Marlins
- Kyle Stowers: 0.299 AVG, 21 HR, 59 RBI
- Otto Lopez: 0.249 AVG, 11 HR, 52 RBI
- Agustin Ramirez: 0.241 AVG, 14 HR, 42 RBI
Team Analysis
San Diego Padres
Coming off a balanced 3-2 streak in their last five games, the San Diego Padres are a team with a knack for maintaining steady rhythm. Their lineup, led by the likes of Manny Machado and Fernando Tatis Jr., has been the backbone of their victories, helping them secure wins even in high-pressure scenarios. Gavin Sheets is another name that has emerged as a constant support, making the Padres a team that can rely on its key players.
While their form is a blend of losses and wins, their recent games have seen a scoring average of 4.6 run per game, which is indicative of their offensive strength. Their performance on the road has been an area of focus, with mixed results that have left room for improvement. Their strength, however, lies in their home matches, where they have put up a stellar performance.
- Batting Average: 0.246
- Total Runs Scored: 392
- Home Runs: 84
- OPS: 0.69
- ERA: 3.63
- WHIP: 1.23
Away Record: 23-27 • Home Record: 31-18
Last 5 Games: 3-2 (4.6 RPG)
Last 10 Games: 6-4 (3.7 RPG)
Miami Marlins
The Miami Marlins have been on an impressive run of late, boasting a 4-1 record in their last five games. They’ve found stability in their lineup with standout performances from Kyle Stowers. Otto Lopez and Agustin Ramirez have also been instrumental in the team’s recent form. The Marlins have shown they are capable of unleashing an offensive storm, as demonstrated by their average of 6.4 runs per game in recent matches.
Although their home form has had its fair share of struggles, their away record stands at an encouraging 24-24. While they have had a consistent run recently, they will need to keep their rhythm intact as they clash with the Padres. With no major injury concerns, the Marlins look to be in good shape for this head-to-head.
- Batting Average: 0.254
- Total Runs Scored: 419
- Home Runs: 90
- OPS: 0.709
- ERA: 4.55
- WHIP: 1.32
Away Record: 24-24 • Home Record: 22-28
Last 5 Games: 4-1 (6.4 RPG)
Last 10 Games: 6-4 (5.3 RPG)
Head-to-Head History
Miami Marlins 1–2 San Diego Padres (Last 3 games)
- 2025-05-28: MIA 10 @ SD 8
- 2025-05-28: MIA 6 @ SD 8
- 2025-05-27: MIA 3 @ SD 4
Over/Under Trends
The San Diego Padres’s recent matchups have seen an average of 6.7 total runs scored per game over their last 7 games, with 2 of these encounters going over the total line.
On the other hand, the Miami Marlins’s recent face-offs have averaged a total of 8.7 runs per game over their last 7 games, with 4 games shooting past the total of 8.0.
Moneyline Betting Prediction
With their recent form, robust lineup, and ability to turn the tide when it matters the most, betting on the San Diego Padres to pull off a win seems to be a value proposition. Their offensive strength backed by their key players is an asset that can thrust them into victory. We confidently back the Padres in this matchup.
Bank on the San Diego Padres at +110 to come up victorious.
Over/Under Prediction
The Miami Marlins are posting an average of 6.4 runs per game in their recent outings, while the San Diego Padres have been managing an average of 4.6. This is key to evaluating the total for this showdown.
Given both teams’ scoring patterns, they are combining to average 11.0 runs per game, well above the total line of 8.0. On that basis, our pick is Over 8.0.
Bookmakers
Your one-stop-shop for the best odds and betting options are: BetOnline.ag, LowVig.ag, Bovada, Caesars, BetUS, DraftKings, MyBookie.ag, FanDuel, BetMGM, BetRivers, Fanatics.
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